日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

FDA Approval Summary: Datopotamab Deruxtecan-dlnk for Treatment of Patients with Unresectable or Metastatic, HR-Positive, HER2-Negative Breast Cancer

FDA批准摘要：Datopotamab Deruxtecan-dlnk用于治疗不可切除或转移性、HR阳性、HER2阴性乳腺癌患者

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-25-1388
Royce, Melanie; Shah, Mirat; Zhang, Lijun; Cheng, Joyce; Bonner, Mary Kate; Pegues, Melissa; Miller, Claudia P; Leu, Lily; Price, Lauren S L; Qiu, Junshan; Yu, Jingyu; Truong, Tien M; Dorff, Sarah E; Yang, Yuching; Zhang, Nailing; Gutierrez-Lugo, Maria; Ricks, Tiffany K; Pierce, William F; Luo, Zhongjun; Kappel, Dana; Goldberg, Kirsten B; Shord, Stacy S; Tang, Shenghui; Bhatnagar, Vishal; Pazdur, Richard; Kluetz, Paul G; Amiri-Kordestani, Laleh
HER2
肿瘤
肿瘤免疫
乳腺癌
发表日期：2025
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FDA Approval Summary: Tovorafenib for Relapsed or Refractory BRAF-Altered Pediatric Low-Grade Glioma

FDA批准摘要：托沃拉非尼用于治疗复发或难治性BRAF突变型儿童低级别胶质瘤

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-24-3439
Singh, Sonia; Bradford, Diana; Chatterjee, Somak; Li, Xiaoxue; Aungst, Stephanie L; Skinner, Amy M; Miller, Claudia P; Kim-McOlash, Sarah; Fourie Zirkelbach, Jeanne; Xiong, Ye; Bi, Youwei; Wang, Ying-Hong; Yang, Yuching; Sun, Jielin; Kraft, Jeffrey; Charlab, Rosane; Shord, Stacy S; Tang, Shenghui; Scepura, Barbara; Bulatao, Ilynn; Udoka, Opeyemi; Saber, Haleh; Rahman, Nam Atiqur; Pazdur, Richard; Singh, Harpreet; Donoghue, Martha; Drezner, Nicole
胶质瘤
BRAF
发表日期：2025
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FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Selecting Optimized Dosages for Registrational Trials

FDA-AACR肿瘤药物产品剂量优化策略：注册试验的最佳剂量选择

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-25-0098
Shord, Stacy S; Chen, Cong; Jin, Jin Y; Van Wart, Scott; Martin, Sarah K; Davidson, Brad A; Liu, Jiang; LoRusso, Patricia M; Oxnard, Geoffrey R
肿瘤
肿瘤免疫
发表日期：2025
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FDA-AACR Strategies for Optimizing Dosages for Oncology Drug Products: Early-Phase Trials Using Innovative Trial Designs and Biomarkers

FDA-AACR 肿瘤药物产品剂量优化策略：采用创新试验设计和生物标志物的早期试验

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-25-1918
Okusanya, Olanrewaju O; Patilea-Vrana, Gabriela I; Sireci, Anthony; Iasonos, Alexia; Davidson, Brad A; Liu, Jiang; Shord, Stacy S; LoRusso, Patricia M; Yap, Timothy A
肿瘤
肿瘤免疫
发表日期：2025
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Dosage Optimization of Pediatric Oncology Products: Our Patients Deserve Better

儿童肿瘤药物剂量优化：我们的患者值得更好的治疗

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-24-4325
Wessel, Kristin M; Drezner, Nicole; Shord, Stacy S; Shah, Mirat; Theoret, Marc R; Donoghue, Martha
肿瘤
肿瘤免疫
发表日期：2025
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FDA Approval Summary: Dabrafenib in Combination with Trametinib for BRAFV600E Mutation-Positive Low-Grade Glioma

FDA批准摘要：达拉非尼联合曲美替尼治疗BRAFV600E突变阳性低级别胶质瘤

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-23-1503
Barbato, Michael I; Nashed, Jeannette; Bradford, Diana; Ren, Yi; Khasar, Sachia; Miller, Claudia P; Zolnik, Banu S; Zhao, Hong; Li, Yangbing; Bi, Youwei; Shord, Stacy S; Amatya, Anup K; Mishra-Kalyani, Pallavi S; Scepura, Barbara; Al-Matari, Raniya A; Pazdur, Richard; Kluetz, Paul G; Donoghue, Martha; Singh, Harpreet; Drezner, Nicole
胶质瘤
BRAF
发表日期：2024
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Perspectives on Drug Development for the Treatment of Chronic Myeloid Leukemia in Pregnant Patients and Patients Who Are Breastfeeding

针对妊娠期和哺乳期慢性粒细胞白血病患者的药物研发展望

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-24-0826
Cortes, Jorge E; Abruzzese, Elisabetta; Cardonick, Elyce H; Hernández-Díaz, Sonia; Gutierrez, Jamie; Sardegna, Mary S; Torres-Chavez, Erica; Dinatale, Miriam; Lerro, Catherine C; Gehrke, Brenda J; Shord, Stacy S; De Claro, R Angelo; Theoret, Marc R; DeMaria, Peter J; Norsworthy, Kelly J
白血病
细胞生物学
粒细胞
发表日期：2024
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Pediatric Cancer Drug Development: Leveraging Insights in Cancer Biology and the Evolving Regulatory Landscape to Address Challenges and Guide Further Progress

儿童癌症药物研发：利用对癌症生物学和不断变化的监管环境的深刻理解来应对挑战并指导未来的发展

期刊:Cold Spring Harbor Perspectives in Medicine
影响因子:10.1
doi:10.1101/cshperspect.a041656
Charlab, Rosane; Leong, Ruby; Shord, Stacy S; Reaman, Gregory H
肿瘤
肿瘤免疫
发表日期：2024
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Utility of Physiologically Based Pharmacokinetic Modeling to Investigate the Impact of Physiological Changes of Pregnancy and Cancer on Oncology Drug Pharmacokinetics

生理药代动力学模型在研究妊娠和癌症生理变化对肿瘤药物药代动力学影响中的应用

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics15122727
Yang, Xinxin; Grimstein, Manuela; Pressly, Michelle; Fletcher, Elimika Pfuma; Shord, Stacy; Leong, Ruby
肿瘤
肿瘤免疫
发表日期：2023
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US Food and Drug Administration embraces using innovation to identify optimized dosages for patients with cancer

美国食品药品监督管理局鼓励利用创新方法来确定癌症患者的最佳剂量。

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.13033
Shord, Stacy S; Zhu, Hao; Liu, Jiang; Rahman, Atiqur; Booth, Brian; Zineh, Issam
肿瘤
肿瘤免疫
发表日期：2023
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