日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hyperactive BMP and Mechanosignaling Remodel Chromatin to Drive Aberrant Osteogenesis in FOP

过度活跃的BMP和机械信号通路重塑染色质,从而驱动FOP中的异常骨生成。

Zhang, Ellen Y; Roberts, Douglas W; Lee, Sang Hyun; Tumenbayar, Bat-Ider; Jung, Jaeun; Rivera, Loreilys Mejías; Jung, Inkyung; Mauck, Robert L; Shore, Eileen M; Heo, Su Chin

An inducible knock-in mouse model of fibrodysplasia ossificans progressiva shows spontaneous formation of heterotopic ossification

一种可诱导的进行性骨化性纤维发育不良症敲入小鼠模型显示出异位骨化的自发形成

Chakkalakal, Salin A; Großmann, Nadine Z; Mejías Rivera, Loreilys; Roberts, Douglas W; Pacifici, Maurizio; Mourkioti, Foteini; Shore, Eileen M

Medical guidelines for fibrodysplasia ossificans progressiva

进行性骨化性纤维发育不良症的医疗指南

Kaplan, Frederick S; Al Mukaddam, Mona; Baujat, Genevieve; Hidalgo Bravo, Alberto; Brown, Matthew; Cali, Amanda; Cho, Tae-Joon; Crowe, Corrie; De Cunto, Carmen L; Delai, Patricia L R; Diecidue, Robert J; Eekhoff, Elisabeth Marelise W; Friedlander, Lisa; Friedman, Clive S; Grunwald, Zvi; Haga, Nobuhiko; Hsiao, Edward C; Keen, Richard; Kitterman, Joseph A; Levy, Charles; Madhuri, Vrisha; Morhart, Rolf; Netelenbos, J Coen; Scott, Christiaan; Shore, Eileen M; Zasloff, Michael; Zhang, Keqin; Pignolo, Robert J

Matrix metalloproteinase-9 deficiency confers resilience in fibrodysplasia ossificans progressiva in a man and mice.

基质金属蛋白酶-9 缺乏症可使人类和小鼠的进行性骨化性纤维发育不良症具有抵抗力

Lounev Vitali, Groppe Jay C, Brewer Niambi, Wentworth Kelly L, Smith Victoria, Xu Meiqi, Schomburg Lutz, Bhargava Pankaj, Al Mukaddam Mona, Hsiao Edward C, Shore Eileen M, Pignolo Robert J, Kaplan Frederick S

Polypeptide Substrate Accessibility Hypothesis: Gain-of-Function R206H Mutation Allosterically Affects Activin Receptor-like Protein Kinase Activity

多肽底物可及性假说:功能获得性R206H突变通过变构作用影响激活素受体样蛋白激酶活性

Groppe, Jay C; Lu, Guorong; Tandang-Silvas, Mary R; Pathi, Anupama; Konda, Shruti; Wu, Jingfeng; Le, Viet Q; Culbert, Andria L; Shore, Eileen M; Wharton, Kristi A; Kaplan, Frederick S

Palovarotene Action Against Heterotopic Ossification Includes a Reduction of Local Participating Activin A-Expressing Cell Populations

帕洛伐罗汀对抗异位骨化的作用机制包括减少局部参与的表达激活素A的细胞群。

Mundy, Christina; Yao, Lutian; Shaughnessy, Kelly A; Saunders, Cheri; Shore, Eileen M; Koyama, Eiki; Pacifici, Maurizio

BMP signaling and skeletal development in fibrodysplasia ossificans progressiva (FOP)

BMP信号传导与进行性骨化性纤维发育不良(FOP)的骨骼发育

Towler, Oscar Will; Shore, Eileen M

Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop

进行性骨化性纤维发育不良:我们取得了哪些成就,现在又处于什么阶段?2015 年洛伦兹研讨会后续报告

de Ruiter, Ruben D; Smilde, Bernard J; Pals, Gerard; Bravenboer, Nathalie; Knaus, Petra; Schoenmaker, Ton; Botman, Esmée; Sánchez-Duffhues, Gonzalo; Pacifici, Maurizio; Pignolo, Robert J; Shore, Eileen M; van Egmond, Marjolein; Van Oosterwyck, Hans; Kaplan, Frederick S; Hsiao, Edward C; Yu, Paul B; Bocciardi, Renata; De Cunto, Carmen Laura; Longo Ribeiro Delai, Patricia; de Vries, Teun J; Hilderbrandt, Susanne; Jaspers, Richard T; Keen, Richard; Koolwijk, Peter; Morhart, Rolf; Netelenbos, Jan C; Rustemeyer, Thomas; Scott, Christiaan; Stockklausner, Clemens; Ten Dijke, Peter; Triffit, James; Ventura, Francesc; Ravazzolo, Roberto; Micha, Dimitra; Eekhoff, Elisabeth M W

Recommendations for Diagnosis and Treatment of Pseudohypoparathyroidism and Related Disorders: An Updated Practical Tool for Physicians and Patients

假性甲状旁腺功能减退症及相关疾病的诊断和治疗建议:面向医生和患者的最新实用工具

Mantovani, Giovanna; Bastepe, Murat; Monk, David; de Sanctis, Luisa; Thiele, Susanne; Ahmed, S Faisal; Bufo, Roberto; Choplin, Timothée; De Filippo, Gianpaolo; Devernois, Guillemette; Eggermann, Thomas; Elli, Francesca M; Garcia Ramirez, Aurora; Germain-Lee, Emily L; Groussin, Lionel; Hamdy, Neveen A T; Hanna, Patrick; Hiort, Olaf; Jüppner, Harald; Kamenický, Peter; Knight, Nina; Le Norcy, Elvire; Lecumberri, Beatriz; Levine, Michael A; Mäkitie, Outi; Martin, Regina; Martos-Moreno, Gabriel Ángel; Minagawa, Manasori; Murray, Philip; Pereda, Arrate; Pignolo, Robert; Rejnmark, Lars; Rodado, Rebeca; Rothenbuhler, Anya; Saraff, Vrinda; Shoemaker, Ashley H; Shore, Eileen M; Silve, Caroline; Turan, Serap; Woods, Philip; Zillikens, M Carola; Perez de Nanclares, Guiomar; Linglart, Agnès

Comment on 'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'

对“帕洛伐罗汀可减少幼年FOP小鼠的异位骨化,但表现出明显的骨骼毒性”的评论

Pacifici, Maurizio; Shore, Eileen M