日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Prions and protein aggregates as pathogens, self-propagating structures, biomarkers, and therapeutic targets

朊病毒和蛋白质聚集体作为病原体、自我复制结构、生物标志物和治疗靶点

Caughey, Byron; Artikis, Efrosini; Shoup, Daniel; Orrú, Christina D; Alam, Parvez; Parveen, Sabiha; King, Samantha; Soukup, Jakub; Hughson, Andrew G; Priola, Suzette A

Chaperone-mediated disaggregation of infectious prions releases particles that seed new prion formation in a strain-specific manner

分子伴侣介导的感染性朊病毒解聚会释放出颗粒,这些颗粒以毒株特异性的方式启动新的朊病毒形成。

Shoup, Daniel; Priola, Suzette A

Evidence against efficient spontaneous disassembly of prions into small oligomers.

有证据表明朊病毒无法有效地自发解离成小寡聚体

Shoup Daniel, Hughson Andrew G, Race Brent, Alam Parvez, Dulebohn Daniel, Priola Suzette A, Caughey Byron

The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease

PINK1/Parkin通路介导的线粒体自噬在朊病毒病中发挥保护作用。

Ward, Anne; Jessop, Forrest; Faris, Robert; Hollister, Jason; Shoup, Daniel; Race, Brent; Bosio, Catharine M; Priola, Suzette A

Bacterial bioconvection confers context-dependent growth benefits and is robust under varying metabolic and genetic conditions

细菌生物对流具有依赖于环境的生长优势,并且在不同的代谢和遗传条件下都表现出稳健性。

Shoup, Daniel; Ursell, Tristan

Cell biology of prion strains in vivo and in vitro

朊病毒株的体内和体外细胞生物学

Shoup, Daniel; Priola, Suzette A

The Impact of Hidden Structure on Aggregate Disassembly by Molecular Chaperones

隐藏结构对分子伴侣介导的聚集体解离的影响

Shoup, Daniel; Roth, Andrew; Puchalla, Jason; Rye, Hays S

Lack of the immune adaptor molecule SARM1 accelerates disease in prion infected mice and is associated with increased mitochondrial respiration and decreased expression of NRF2

免疫衔接分子SARM1的缺失会加速朊病毒感染小鼠的疾病进展,并与线粒体呼吸作用增强和NRF2表达降低有关。

Ward, Anne; Jessop, Forrest; Faris, Robert; Shoup, Daniel; Bosio, Catharine M; Peterson, Karin E; Priola, Suzette A

Development and application of multicolor burst analysis spectroscopy

多色突发分析光谱技术的发展与应用

Shoup, Daniel; Roth, Andrew; Thapa, Rajan; Puchalla, Jason; Rye, Hays S

Altered distribution, aggregation, and protease resistance of cellular prion protein following intracranial inoculation

颅内接种后细胞朊病毒蛋白的分布、聚集和蛋白酶抗性发生改变

Ward, Anne; Hollister, Jason R; Choi, Young Pyo; Race, Brent; Williams, Katie; Shoup, Daniel W; Moore, Roger A; Priola, Suzette A