日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Correction to "DNA-Programmable Protein Degradation: Dynamic Control of Proteolysis-Targeting Chimera Activity via DNA Hybridization and Strand Displacement"

对“DNA可编程蛋白质降解：通过DNA杂交和链置换动态控制蛋白水解靶向嵌合体活性”一文的更正

期刊:JACS Au
影响因子:8.7
doi:10.1021/jacsau.5c01700
Kashyap, Disha; Haider, Shozeb; Milne, Thomas A; Booth, Michael J
发表日期：2026
文献求助 收藏

Cryptic Binding Pockets in PDC‑3 β‑Lactamase Modulate Resistance Profiles

PDC-3 β-内酰胺酶中的隐蔽结合口袋调节耐药谱

期刊:JACS Au
影响因子:8.7
doi:10.1021/jacsau.5c01707
Chen, Shuang; Attana, Fedaa; Hujer, Andrea M; Bethel, Christopher R; Taracila, Magdalena A; Bonomo, Robert A; Haider, Shozeb
发表日期：2026
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Structural and Kinetic Basis for the Rational Design of Next-Generation β-Lactamase Inhibitors

下一代β-内酰胺酶抑制剂合理设计的结构和动力学基础

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c03315
Chen, Shuang; Yu, Muchen; Xu, Manming; Decherchi, Sergio; Taracila, Magdalena A; Hujer, Andrea M; Bethel, Christopher R; Bonomo, Robert A; Haider, Shozeb
发表日期：2026
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Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase

Ω环突变通过调节PDC-3 β-内酰胺酶中的氢键网络来控制活性位点的动力学。

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.107688
Chen, Shuang; Mack, Andrew R; Hujer, Andrea M; Bethel, Christopher R; Bonomo, Robert A; Haider, Shozeb
发表日期：2026
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Proposal of metagenomic-origin LRA-5 as a precursor of active β-lactamases through Tyr69Gln and Val166Glu amino acid substitutions: a functional and structural analysis

通过Tyr69Gln和Val166Glu氨基酸替换，提出宏基因组来源的LRA-5作为活性β-内酰胺酶的前体：功能和结构分析

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00675-25
D'Amico González, Gabriela; Rodríguez, María Margarita; Penzotti, Pedro; Brunetti, Florencia; Ghiglione, Barbara; Moe, Luke A; Centrón, Daniela; Gutkind, Gabriel; Gao, Lin; Haider, Shozeb; Powers, Rachel A; Klinke, Sebastián; Power, Pablo
发表日期：2026
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Affinity-selected peptide ligands specifically bind i-motif DNA and modulate c-Myc gene expression

亲和力筛选的肽配体特异性结合i-motif DNA并调节c-Myc基因表达。

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkaf1052
Guneri, Dilek; Rosonovski, Summer; Alexandrou, Effrosyni; Chen, Shuang; King, Jessica; Waudby, Christopher A; Haider, Shozeb; Morris, Christoper J; Waller, Zoë A E
发表日期：2025
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De novo variants disrupt an LDB1-regulated transcriptional network in congenital ventriculomegaly

新生变异破坏了先天性脑室扩大症中 LDB1 调控的转录网络

期刊:Brain
影响因子:11.7
doi:10.1093/brain/awae395
Allington, Garrett; Mehta, Neel H; Dennis, Evan; Mekbib, Kedous Y; Reeves, Benjamin; Kiziltug, Emre; Chen, Shuang; Zhao, Shujuan; Duy, Phan Q; Saleh, Maha; Ang, Lee C; Fan, Baojian; Nelson-Williams, Carol; Moreno-de-Luca, Andrés; Haider, Shozeb; Lifton, Richard P; Alper, Seth L; McGee, Stephen; Jin, Sheng Chih; Kahle, Kristopher T
信号转导
LDB1
神经科学
发表日期：2025
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DNA-Programmable Protein Degradation: Dynamic Control of Proteolysis-Targeting Chimera Activity via DNA Hybridization and Strand Displacement

DNA可编程蛋白质降解：通过DNA杂交和链置换动态控制蛋白水解靶向嵌合体活性

期刊:JACS Au
影响因子:8.7
doi:10.1021/jacsau.5c00422
Kashyap, Disha; Haider, Shozeb; Milne, Thomas A; Booth, Michael J
发表日期：2025
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Selective molecular inhibition of the HDAC6 ZnF-UBP binding domain impairs multiple myeloma cell function.

选择性抑制 HDAC6 ZnF-UBP 结合域可损害多发性骨髓瘤细胞功能

期刊:Cell Death Discovery
影响因子:7
doi:10.1038/s41420-025-02465-1
Rincón Rafael, F Coira Isabel, Richieu Antoine, Attana Fedaa, Urwyler Muriel, Haider Shozeb, Bourquin Carole, Bertrand Philippe, Cuendet Muriel
细胞生物学
发表日期：2025
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Functionally important residues from graph analysis of coevolved dynamic couplings

通过对共演化动态耦合的图分析，筛选出具有重要功能的残基

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.105005
Xu, Manming; Dantu, Sarath Chandra; Garnett, James A; Bonomo, Robert A; Pandini, Alessandro; Haider, Shozeb
发表日期：2025
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