日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Simulations and active learning enable efficient identification of an experimentally-validated broad coronavirus inhibitor.

模拟和主动学习能够有效地识别经实验验证的广谱冠状病毒抑制剂

Elez Katarina, Hempel Tim, Shrimp Jonathan H, Moor Nicole, Raich Lluís, Rocha Cheila, Winter Robin, Le Tuan, Pöhlmann Stefan, Hoffmann Markus, Hall Matthew D, Noé Frank

Mass spectrometry-guided discovery of novel GCPII inhibitor scaffolds

质谱引导下新型GCPII抑制剂骨架的发现

Wiseman, Robyn; Thomas, Ajit G; Janiszewski, John; Hoxie, Nate; Lee, Chae Bin; Wu, Ying; Tsukamoto, Takashi; Ye, Lin; Ronzetti, Michael; Shrimp, Jonathan H; Adderley, Davina; Rai, Ganesha; Rais, Rana; Alt, Jesse; Hall, Matthew D; Hu, Xin; Kales, Stephen C; Slusher, Barbara S

Notes on AEMS methods development for high throughput experimentation in drug discovery

关于用于药物发现高通量实验的AEMS方法开发的说明

Verma, Meghav; Hoxie, Nate; Janiszewski, John; Bonney, Charles; Hall, Matthew D; Michael, Sam; Covey, Tom; Shrimp, Jonathan H

Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy.

动态成像显示肿瘤中 LDH 抑制可导致体内代谢快速重编程,并对联合疗法产生敏感性

Oshima Nobu, Ishida Ryo, Kishimoto Shun, Beebe Kristin, Brender Jeffrey R, Yamamoto Kazutoshi, Urban Daniel, Rai Ganesha, Johnson Michelle S, Benavides Gloria, Squadrito Giuseppe L, Crooks Dan, Jackson Joseph, Joshi Abhinav, Mott Bryan T, Shrimp Jonathan H, Moses Michael A, Lee Min-Jung, Yuno Akira, Lee Tobie D, Hu Xin, Anderson Tamara, Kusewitt Donna, Hathaway Helen H, Jadhav Ajit, Picard Didier, Trepel Jane B, Mitchell James B, Stott Gordon M, Moore William, Simeonov Anton, Sklar Larry A, Norenberg Jeffrey P, Linehan W Marston, Maloney David J, Dang Chi V, Waterson Alex G, Hall Matthew, Darley-Usmar Victor M, Krishna Murali C, Neckers Leonard M

Bioorthogonal pro-metabolites for profiling short chain fatty acylation

用于分析短链脂肪酰化的生物正交前代谢物

Sinclair, Wilson R; Shrimp, Jonathan H; Zengeya, Thomas T; Kulkarni, Rhushikesh A; Garlick, Julie M; Luecke, Hans; Worth, Andrew J; Blair, Ian A; Snyder, Nathaniel W; Meier, Jordan L

Chemical Control of a CRISPR-Cas9 Acetyltransferase

CRISPR-Cas9乙酰转移酶的化学控制

Shrimp, Jonathan H; Grose, Carissa; Widmeyer, Stephanie R T; Thorpe, Abigail L; Jadhav, Ajit; Meier, Jordan L

Profiling Cytidine Acetylation with Specific Affinity and Reactivity.

具有特异性亲和力和反应性的胞苷乙酰化分析

Sinclair Wilson R, Arango Daniel, Shrimp Jonathan H, Zengeya Thomas T, Thomas Justin M, Montgomery David C, Fox Stephen D, Andresson Thorkell, Oberdoerffer Shalini, Meier Jordan L

Characterizing the Covalent Targets of a Small Molecule Inhibitor of the Lysine Acetyltransferase P300

赖氨酸乙酰转移酶 P300 小分子抑制剂的共价靶点表征

Shrimp, Jonathan H; Sorum, Alexander W; Garlick, Julie M; Guasch, Laura; Nicklaus, Marc C; Meier, Jordan L