Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo
抑制 CDK8/19 介导激酶可增强 HER2 靶向药物的疗效,并在体外和体内克服对这些药物的耐药性。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2201073119
Ding, Xiaokai; Sharko, Amanda C; McDermott, Martina S J; Schools, Gary P; Chumanevich, Alexander; Ji, Hao; Li, Jing; Zhang, Li; Mack, Zachary T; Sikirzhytski, Vitali; Shtutman, Michael; Ivers, Laura; O'Donovan, Norma; Crown, John; Győrffy, Balázs; Chen, Mengqian; Roninson, Igor B; Broude, Eugenia V