Loss of histone methyltransferase Smyd3 triggers WAT browning and adaptive thermogenesis via enhancing PPARγ expression in a H4K20me3-dependent manner.
组蛋白甲基转移酶 Smyd3 的缺失通过以 H4K20me3 依赖的方式增强 PPARα 表达来触发 WAT 褐变和适应性产热
期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-025-07072-3
Shu Meiling, Ma Youzhen, Zhao Dandan, Meng Chen, Chen Lang, Wang Leihao, Liu Jing, Yang Di
