日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: phase 1 AMPLIFY-201 trial final results

靶向淋巴结的mKRAS特异性两亲性疫苗治疗胰腺癌和结直肠癌：AMPLIFY-201 I期试验最终结果

期刊:Nature Medicine
影响因子:58.7
doi:10.1038/s41591-025-03876-4
Zev A Wainberg ，Colin D Weekes ，Muhammad Furqan ，Pashtoon M Kasi ，Craig E Devoe ，Alexis D Leal ，Vincent Chung ，James R Perry ，Thian Kheoh ，Lisa K McNeil ，Esther Welkowsky ，Peter C DeMuth ，Christopher M Haqq ，Shubham Pant # ，Eileen M O'Reilly #
肿瘤
肠癌
胰腺癌
LIF
MPL
KRAS
发表日期：2025
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A nnU-Net-based automatic segmentation of FCD type II lesions in 3D FLAIR MRI images

基于 nnU-Net 的 3D FLAIR MRI 图像中 FCD II 型病变的自动分割

期刊:Frontiers in Artificial Intelligence
影响因子:4.7
doi:10.3389/frai.2025.1601815
Joshi, Shubham; Pant, Millie; Malhotra, Arnav; Deep, Kusum; Snasel, Vaclav
3D/类器官
发表日期：2025
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Diagnostic Challenges and Recovery of First Tarsometatarsal Joint Tuberculosis Extending to Medial Cuneiform and First Metatarsal: A Rare Case Report

第一跖跗关节结核累及内侧楔骨和第一跖骨的诊断挑战及康复：一例罕见病例报告

期刊:Clinical Case Reports
影响因子:0.6
doi:10.1002/ccr3.70799
Sweekar, Dahal; Omkar, Bist; Sriram, Khati; Sunil, Bhatta; Maya, Upadhyaya; Shubham, Pant
发表日期：2025
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Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial

淋巴结靶向、mKRAS特异性两亲性疫苗在胰腺癌和结直肠癌中的应用：AMPLIFY-201 I期试验

期刊:Nature Medicine
影响因子:58.7
doi:10.1038/s41591-023-02760-3
Shubham Pant ，Zev A Wainberg ，Colin D Weekes ，Muhammad Furqan ，Pashtoon M Kasi ，Craig E Devoe ，Alexis D Leal ，Vincent Chung ，Olca Basturk ，Haley VanWyk ，Amy M Tavares ，Lochana M Seenappa ，James R Perry ，Thian Kheoh ，Lisa K McNeil ，Esther Welkowsky ，Peter C DeMuth ，Christopher M Haqq ，Eileen M O'Reilly
胰腺癌
LIF
MPL
肿瘤
肠癌
肿瘤免疫
RAS
发表日期：2024
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Phase 1 dose expansion and biomarker study assessing first-in-class tumor microenvironment modulator VT1021 in patients with advanced solid tumors

期剂量扩展和生物标志物研究评估了首创肿瘤微环境调节剂 VT1021 对晚期实体瘤患者的疗效

期刊:Commun Med (Lond)
影响因子:
doi:10.1038/s43856-024-00520-z
Jian Jenny Chen, Melanie Y Vincent, Dale Shepard, David Peereboom, Devalingam Mahalingam, James Battiste, Manish R Patel, Dejan Juric, Patrick Y Wen, Andrea Bullock, Jennifer Eva Selfridge, Shubham Pant, Joyce Liu, Wendy Li, Susanne Fyfe, Suming Wang, Victor Zota, James Mahoney, Randolph S Watnick, 
肿瘤
发表日期：2024
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Preclinical study and parallel phase II trial evaluating antisense STAT3 oligonucleotide and checkpoint blockade for advanced pancreatic, non-small cell lung cancer and mismatch repair-deficient colorectal cancer

临床前研究和平行 II 期试验评估反义 STAT3 寡核苷酸和检查点阻断对晚期胰腺癌、非小细胞肺癌和错配修复缺陷型结直肠癌的疗效

期刊:
影响因子:
doi:10.1136/bmjonc-2023-000133
Chad Tang #, Genevieve P Hartley #, Coline Couillault, Ying Yuan, Heather Lin, Courtney Nicholas, Anupallavi Srinivasamani, James Dai, Ecaterina E Ileana Dumbrava, Siqing Fu, Daniel D Karp, Aung Naing, Sarina A Piha-Paul, Jordi Rodon Ahnert, Shubham Pant, Vivek Subbiah, Timonthy A Yap, Apostolia M T
免疫
细胞生物学
肠癌
肺癌
胰腺癌
肿瘤细胞
Checkpoint
发表日期：2024
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Single-Cell Sequencing Reveals Trajectory of Tumor-Infiltrating Lymphocyte States in Pancreatic Cancer

单细胞测序揭示胰腺癌肿瘤浸润淋巴细胞状态的轨迹

期刊:Cancer Discovery
影响因子:29.7
doi:10.1158/2159-8290.CD-21-1248
Aislyn Schalck #, Donastas Sakellariou-Thompson #, Marie-Andrée Forget, Emi Sei, Tara G Hughes, Alexandre Reuben, Shanshan Bai, Min Hu, Tapsi Kumar, Mark W Hurd, Matthew H G Katz, Ching-Wei D Tzeng, Shubham Pant, Milind Javle, David R Fogelman, Anirban Maitra, Cara L Haymaker, Michael P Kim #, Nicho
代谢
肿瘤
胰腺癌
肿瘤细胞
其它细胞
发表日期：2022
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3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma

基于类器官平台的 3D 成像分析指导胰腺导管腺癌的个性化治疗

期刊:Journal of Clinical Investigation
影响因子:13.3
doi:10.1172/JCI151604
Ya'an Kang, Jenying Deng, Jianhua Ling, Xinqun Li, Yi-Ju Chiang, Eugene J Koay, Huamin Wang, Jared K Burks, Paul J Chiao, Mark W Hurd, Manoop S Bhutani, Jeffrey H Lee, Brian R Weston, Anirban Maitra, Naruhiko Ikoma, Ching-Wei D Tzeng, Jeffrey E Lee, Ronald A DePinho, Robert A Wolff, Shubham Pant, Fl
肿瘤
胰腺癌
发表日期：2022
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A first-in-human phase 1/2 study of FGF401 and combination of FGF401 with spartalizumab in patients with hepatocellular carcinoma or biomarker-selected solid tumors

FGF401 以及 FGF401 与 spartalizumab 联合治疗肝细胞癌或生物标志物选定的实体瘤患者的首次人体 1/2 期研究

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:11.4
doi:10.1186/s13046-022-02383-5
Stephen L Chan, Martin Schuler, Yoon-Koo Kang, Chia-Jui Yen, Julien Edeline, Su Pin Choo, Chia-Chi Lin, Takuji Okusaka, Karl-Heinz Weiss, Teresa Macarulla, Stéphane Cattan, Jean-Frederic Blanc, Kyung-Hun Lee, Michela Maur, Shubham Pant, Masatoshi Kudo, Eric Assenat, Andrew X Zhu, Thomas Yau, Ho Yeon
免疫
细胞生物学
肝癌
肿瘤细胞
发表日期：2022
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Emergence of mTOR mutation as an acquired resistance mechanism to AKT inhibition, and subsequent response to mTORC1/2 inhibition

mTOR 突变作为对 AKT 抑制的获得性耐药机制出现，以及随后对 mTORC1/2 抑制的反应

期刊:npj Precision Oncology
影响因子:6.8
doi:10.1038/s41698-021-00240-w
Niamh Coleman, Vivek Subbiah, Shubham Pant, Keyur Patel, Sinchita Roy-Chowdhuri, Sireesha Yedururi, Amber Johnson, Timothy A Yap, Jordi Rodon, Kenna Shaw, Funda Meric-Bernstam
信号转导
PI3K/Akt
mTOR
发表日期：2021
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