文献库，生知库 | 链接生命科学的每一步

Basak, Debashree; Ghosh, Puspendu; Gautam, Anupam; Sarkar, Ishita; Bhoumik, Arpita; Chowdhury, Soham; Mahanti, Shaun; Mandal, Anwesha; Chakraborty, Rajeswari; Kar, Anwesha; Chowdhury, Snehanshu; Kumar, Krishna; Barman, Shubhrajit; Ganesan, Senthil Kumar; Chakrabarti, Saikat; Paul, Sandip; Chatterjee, Shilpak

信号转导

CD8

代谢

NON-REDUNDANT ROLES OF COPPER TRANSPORTERS ATP7A AND ATP7B IN NORADRENERGIC SIGNALING

铜转运蛋白ATP7A和ATP7B在去甲肾上腺素能信号传导中不可替代的作用

期刊:

影响因子:

doi:10.64898/2026.01.15.699802

Roy, Shubhrajit; Wang, Yu; Aja, Susan; Sinha, Niharika; Crawford, Andrew; MacRenaris, Keith; Wade, Alexa; Kim, Kyungdo; Muchenditsi, Abigael; Torres-Hernandez, Lauryn; Na, Chan Hyun; Kralli, Anastasia; Petris, Michael; Taylor, Anna; O'Halloran, Thomas; Tressler, Cay; Glunde, Kristine; Lutsenko, Svetlana

Mammalian copper homeostasis: physiological roles and molecular mechanisms

哺乳动物铜稳态：生理作用和分子机制

期刊:Physiological Reviews

影响因子:28.7

doi:10.1152/physrev.00011.2024

Lutsenko, Svetlana; Roy, Shubhrajit; Tsvetkov, Peter

发表日期：2025

文献求助收藏

Unveiling ferroptosis genes and inhibitors in diabetic retinopathy through single-cell analysis and docking simulations

通过单细胞分析和分子对接模拟揭示糖尿病视网膜病变中的铁死亡基因和抑制剂

期刊:Biochemistry and Biophysics Reports

影响因子:2.2

doi:10.1016/j.bbrep.2025.101932

Ahamad Khan, Md Maqsood; Ganguly, Ananya; Barman, Shubhrajit; Das, Chirasmita; Ganesan, Senthil Kumar

Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard

Slc25a3依赖的铜转运控制闪烁诱导的Opa1加工，从而保护线粒体。

期刊:Developmental Cell

影响因子:10.7

doi:10.1016/j.devcel.2024.06.008

Daisuke Murata ,Shubhrajit Roy ,Svetlana Lutsenko ,Miho Iijima ,Hiromi Sesaki

线粒体

发表日期：2024

文献求助收藏

CD38-RyR2 axis-mediated signaling impedes CD8(+) T cell response to anti-PD1 therapy in cancer

CD38-RyR2轴介导的信号传导会抑制癌症中CD8(+) T细胞对PD-1抑制剂的反应。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2315989121

Kar, Anwesha; Ghosh, Puspendu; Gautam, Anupam; Chowdhury, Snehanshu; Basak, Debashree; Sarkar, Ishita; Bhoumik, Arpita; Barman, Shubhrajit; Chakraborty, Paramita; Mukhopadhyay, Asima; Mehrotra, Shikhar; Ganesan, Senthil Kumar; Paul, Sandip; Chatterjee, Shilpak

Mechanism of Cu entry into the brain: many unanswered questions

铜进入大脑的机制：许多问题尚未解答

期刊:Neural Regeneration Research

影响因子:6.7

doi:10.4103/1673-5374.393107

Roy, Shubhrajit; Lutsenko, Svetlana

神经科学

发表日期：2024

文献求助收藏

Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain

Atp7b 依赖性脉络丛功能障碍导致小鼠大脑发育过程中出现短暂性铜缺乏和代谢变化

期刊:PLoS Genetics

影响因子:

doi:10.1371/journal.pgen.1010558

Clorissa L Washington-Hughes, Shubhrajit Roy, Herana Kamal Seneviratne, Senthilkumar S Karuppagounder, Yulemni Morel, Jace W Jones, Alex Zak, Tong Xiao, Tatiana N Boronina, Robert N Cole, Namandjé N Bumpus, Christopher J Chang, Ted M Dawson, Svetlana Lutsenko

α-lipoic acid ameliorates consequences of copper overload by up-regulating selenoproteins and decreasing redox misbalance

α-硫辛酸通过上调硒蛋白和减少氧化还原失衡来改善铜超载的后果

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.2305961120

Ekaterina Kabin, Yixuan Dong #, Shubhrajit Roy #, Julia Smirnova, Joshua W Smith, Martina Ralle, Kelly Summers, Haojun Yang, Som Dev, Yu Wang, Benjamin Devenney, Robert N Cole, Peep Palumaa, Svetlana Lutsenko

信号转导

发表日期：2023

文献求助收藏

Heterogeneous nuclear ribonucleoprotein hnRNPA2/B1 regulates the abundance of the copper-transporter ATP7A in an isoform-dependent manner

异质核糖核蛋白hnRNPA2/B1以亚型依赖的方式调节铜转运蛋白ATP7A的丰度。

期刊:Frontiers in Molecular Biosciences

影响因子:4

doi:10.3389/fmolb.2022.1067490

McCann, Courtney J; Hasan, Nesrin M; Padilla-Benavides, Teresita; Roy, Shubhrajit; Lutsenko, Svetlana

ATP7A

发表日期：2022

文献求助收藏

S1P-S1PR1 signaling impairs CD8(+) T cell metabolism and effector function in tumors

S1P-S1PR1信号通路会损害肿瘤中CD8(+) T细胞的代谢和效应功能。

NON-REDUNDANT ROLES OF COPPER TRANSPORTERS ATP7A AND ATP7B IN NORADRENERGIC SIGNALING

铜转运蛋白ATP7A和ATP7B在去甲肾上腺素能信号传导中不可替代的作用

Mammalian copper homeostasis: physiological roles and molecular mechanisms

哺乳动物铜稳态：生理作用和分子机制

Unveiling ferroptosis genes and inhibitors in diabetic retinopathy through single-cell analysis and docking simulations

通过单细胞分析和分子对接模拟揭示糖尿病视网膜病变中的铁死亡基因和抑制剂

Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard

Slc25a3依赖的铜转运控制闪烁诱导的Opa1加工，从而保护线粒体。

CD38-RyR2 axis-mediated signaling impedes CD8(+) T cell response to anti-PD1 therapy in cancer

CD38-RyR2轴介导的信号传导会抑制癌症中CD8(+) T细胞对PD-1抑制剂的反应。

Mechanism of Cu entry into the brain: many unanswered questions

铜进入大脑的机制：许多问题尚未解答

Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brain

Atp7b 依赖性脉络丛功能障碍导致小鼠大脑发育过程中出现短暂性铜缺乏和代谢变化

α-lipoic acid ameliorates consequences of copper overload by up-regulating selenoproteins and decreasing redox misbalance

α-硫辛酸通过上调硒蛋白和减少氧化还原失衡来改善铜超载的后果

Heterogeneous nuclear ribonucleoprotein hnRNPA2/B1 regulates the abundance of the copper-transporter ATP7A in an isoform-dependent manner

异质核糖核蛋白hnRNPA2/B1以亚型依赖的方式调节铜转运蛋白ATP7A的丰度。