日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

How interdiction of inositol pyrophosphate catabolism perturbs the fission yeast response to phosphate starvation

抑制肌醇焦磷酸分解代谢如何扰乱裂殖酵母对磷酸盐饥饿的反应

Babor, Jill; Sanchez, Ana M; Prucker, Isabel; Jessen, Henning J; Schwer, Beate; Shuman, Stewart

Structure of an initiation complex of mycobacterial helicase-nuclease AdnAB at a blunt double-strand break reveals local melting that engages the 3' tracking strand at the ratchet pawl of the helicase motor

分枝杆菌解旋酶-核酸酶AdnAB起始复合物在平末端双链断裂处的结构揭示了局部解旋,该解旋酶马达的棘爪与3'追踪链结合。

Warren, Garrett M; Jason de la Cruz, M; Goldgur, Yehuda; Shuman, Stewart

Transporter-Driven Glycerophosphocholine (GPC) Toxicity Is Conserved from Fission Yeast to Budding Yeast: Roles for Inositol Pyrophosphates and Gde1 Regulation in Fission Yeast

转运蛋白驱动的甘油磷酸胆碱(GPC)毒性在裂殖酵母和出芽酵母中是保守的:肌醇焦磷酸和Gde1调控在裂殖酵母中的作用

Hrach, Victoria Lee; Schwer, Beate; Vitek, Lane; Borowicz, Michael; Innokentev, Aleksei; Sanchez, Ana M; Singer, Justin R; Shuman, Stewart; Patton-Vogt, Jana

Ifn1 is an intracellular GMP 5'-nucleotidase induced during the fission yeast response to phosphate starvation

Ifn1 是一种细胞内 GMP 5'-核苷酸酶,在裂殖酵母应对磷酸盐饥饿时被诱导表达。

Innokentev, Aleksei; Schwer, Beate; Shuman, Stewart

In vivo nucleotide excision repair by mycobacterial UvrD1 requires ATP hydrolysis but does not depend on cysteine disulfide-mediated dimerization and DNA unwinding

分枝杆菌UvrD1介导的体内核苷酸切除修复需要ATP水解,但不依赖于半胱氨酸二硫键介导的二聚化和DNA解旋。

Warren, Garrett M; Shuman, Stewart

Structural basis for sensitivity and acquired resistance of fungal cap guanine-N7 methyltransferases to the antifungal antibiotic sinefungin

真菌帽鸟嘌呤-N7甲基转移酶对抗菌抗生素西尼芬净的敏感性和获得性耐药性的结构基础

Nilson, Daniel J; Schwer, Beate; Almo, Steven C; Shuman, Stewart; Ghosh, Agnidipta

Desthiobiotin (DTB)-modified and TAMRA-modified 2″OMeNAD(+) are RNA 2'-phosphotransferase (Tpt1) poisons that enable affinity-tagging and fluorescence-tagging of internal RNA 2'-phosphate groups

经脱硫生物素 (DTB) 和 TAMRA 修饰的 2″OMeNAD(+) 是 RNA 2'-磷酸转移酶 (Tpt1) 抑制剂,可用于对 RNA 内部 2'-磷酸基团进行亲和标记和荧光标记。

Kasprzyk, Renata; Ghosh, Shreya; Shuman, Stewart

Genetic suppression of precocious transcription termination identifies mutations in essential subunits of the fission yeast cleavage and polyadenylation machinery

通过基因手段抑制过早的转录终止,可以鉴定出裂殖酵母切割和多聚腺苷酸化机制关键亚基的突变。

Innokentev, Aleksei; Sanchez, Ana M; Bednor, Lauren; Babor, Jill; Schwer, Beate; Shuman, Stewart

Structures of RNA phosphotransferase Tpt1 reveal distinct binding modes for an RNA 2'-PO(4) splice junction versus a 5'-PO(4) mononucleotide

RNA磷酸转移酶Tpt1的结构揭示了其对RNA 2'-PO(4)剪接位点和5'-PO(4)单核苷酸的不同结合模式

Jacewicz, Agata; Damha, Masad J; Shuman, Stewart

Tandem inactivation of inositol pyrophosphatases Asp1, Siw14, and Aps1 illuminates functional redundancies in inositol pyrophosphate catabolism in fission yeast

肌醇焦磷酸酶 Asp1、Siw14 和 Aps1 的串联失活揭示了裂殖酵母中肌醇焦磷酸分解代谢的功能冗余

Schwer, Beate; Prucker, Isabel; Sanchez, Ana M; Babor, Jill; Jessen, Henning J; Shuman, Stewart