日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

HLA B*5701 与 HIV 感染长期无进展者亚群中病毒复制的限制高度相关

Migueles, S A; Sabbaghian, M S; Shupert, W L; Bettinotti, M P; Marincola, F M; Martino, L; Hallahan, C W; Selig, S M; Schwartz, D; Sullivan, J; Connors, M

Resistance to replication of human immunodeficiency virus challenge in SCID-Hu mice engrafted with peripheral blood mononuclear cells of nonprogressors is mediated by CD8(+) T cells and associated with a proliferative response to p24 antigen.

在移植了非进展者外周血单核细胞的 SCID-Hu 小鼠中,对人类免疫缺陷病毒攻击的复制的抵抗力是由 CD8(+) T 细胞介导的,并且与对 p24 抗原的增殖反应有关

de Quiros J C, Shupert W L, McNeil A C, Gea-Banacloche J C, Flanigan M, Savage A, Martino L, Weiskopf E E, Imamichi H, Zhang Y M, Adelsburger J, Stevens R, Murphy P M, Zimmerman P A, Hallahan C W, Davey R T Jr, Connors M