Addition of Lauryldimethylamine N-Oxide (LDAO) to a Copper-Free Click Chemistry Reaction Improves the Conjugation Efficiency of a Cell-Free Generated CRM197 Variant to Clinically Important Streptococcus pneumoniae Serotypes

将十二烷基二甲胺 N-氧化物 (LDAO) 添加到无铜点击化学反应中可提高无细胞生成的 CRM197 变体与临床重要肺炎链球菌血清型的结合效率