日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

AI-based discovery and cryoEM structural elucidation of a K(ATP) channel pharmacochaperone

基于人工智能的K(ATP)通道药理伴侣蛋白的发现和冷冻电镜结构解析

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.103159
Elsheikh, Assmaa; Driggers, Camden M; Truong, Ha H; Yang, Zhongying; Allen, John; Henriksen, Niel M; Walczewska-Szewc, Katarzyna; Shyng, Show-Ling
发表日期：2025
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Identification and rescue of congenital hyperinsulinism-associated ABCC8 mutations that impair K(ATP) channel trafficking

鉴定并挽救先天性高胰岛素血症相关的ABCC8突变，这些突变会损害K(ATP)通道的转运。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110779
ElSheikh, Assmaa; Kuo, Yi-Ying; Boodhansingh, Kara E; Yang, Zhongying; Stanley, Charles A; De Leon, Diva D; Shyng, Show-Ling
免疫/内分泌
发表日期：2025
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Identification and Rescue of Congenital Hyperinsulinism-Associated ABCC8 Mutations that Impair K(ATP) Channel Trafficking

识别和挽救先天性高胰岛素血症相关ABCC8突变，这些突变会损害K(ATP)通道的转运

期刊:
影响因子:
doi:10.1101/2025.05.18.654760
ElSheikh, Assmaa; Kuo, Yi-Ying; Boodhansingh, Kara E; Yang, Zhongying; Stanley, Charles A; De Leon, Diva D; Shyng, Show-Ling
免疫/内分泌
发表日期：2025
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K(ATP) channels in focus: Progress toward a structural understanding of ligand regulation

聚焦K(ATP)通道：配体调控结构机制研究进展

期刊:Current Opinion in Structural Biology
影响因子:7
doi:10.1016/j.sbi.2023.102541
Martin, Gregory M; Patton, Bruce L; Shyng, Show-Ling
信号转导
发表日期：2023
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Mechanistic insights on KATP channel regulation from cryo-EM structures.

从冷冻电镜结构中揭示KATP通道调控的机制

期刊:Journal of General Physiology
影响因子:2.9
doi:10.1085/jgp.202113046
Driggers Camden M, Shyng Show-Ling
信号转导
发表日期：2023
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Localized islet nuclear enlargement hyperinsulinism (LINE-HI) due to ABCC8 and GCK mosaic mutations

由ABCC8和GCK嵌合突变引起的局部胰岛核增大高胰岛素血症（LINE-HI）

期刊:European Journal of Endocrinology
影响因子:5.2
doi:10.1530/EJE-21-1095
Boodhansingh, Kara E; Yang, Zhongying; Li, Changhong; Chen, Pan; Lord, Katherine; Becker, Susan A; States, Lisa J; Adzick, N Scott; Bhatti, Tricia; Shyng, Show-Ling; Ganguly, Arupa; Stanley, Charles A; De Leon, Diva D
免疫/内分泌
发表日期：2022
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Subcellular trafficking and endocytic recycling of K(ATP) channels

K(ATP)通道的亚细胞运输和内吞循环

期刊:American Journal of Physiology-Cell Physiology
影响因子:4.7
doi:10.1152/ajpcell.00099.2022
Yang, Hua-Qian; Echeverry, Fabio A; ElSheikh, Assmaa; Gando, Ivan; Anez Arredondo, Sophia; Samper, Natalie; Cardozo, Timothy; Delmar, Mario; Shyng, Show-Ling; Coetzee, William A
细胞生物学
发表日期：2022
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Ligand-mediated Structural Dynamics of a Mammalian Pancreatic K(ATP) Channel.

哺乳动物胰腺K(ATP)通道的配体介导结构动力学

期刊:Journal of Molecular Biology
影响因子:4.5
doi:10.1016/j.jmb.2022.167789
Sung Min Woo, Driggers Camden M, Mostofian Barmak, Russo John D, Patton Bruce L, Zuckerman Daniel M, Shyng Show-Ling
发表日期：2022
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Vascular K(ATP) channel structural dynamics reveal regulatory mechanism by Mg-nucleotides

血管K(ATP)通道结构动力学揭示Mg核苷酸的调控机制

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2109441118
Sung, Min Woo; Yang, Zhongying; Driggers, Camden M; Patton, Bruce L; Mostofian, Barmak; Russo, John D; Zuckerman, Daniel M; Shyng, Show-Ling
信号转导
发表日期：2021
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Functional characterization of ABCC8 variants of unknown significance based on bioinformatics predictions, splicing assays, and protein analyses: Benefits for the accurate diagnosis of congenital hyperinsulinism

基于生物信息学预测、剪接分析和蛋白质分析对意义不明的ABCC8变异体进行功能表征：有利于先天性高胰岛素血症的准确诊断

期刊:Human Mutation
影响因子:3.7
doi:10.1002/humu.24164
Saint-Martin, Cécile; Cauchois-Le Mière, Marine; Rex, Emily; Soukarieh, Omar; Arnoux, Jean-Baptiste; Buratti, Julien; Bouvet, Delphine; Frébourg, Thierry; Gaildrat, Pascaline; Shyng, Show-Ling; Bellanné-Chantelot, Christine; Martins, Alexandra
免疫/内分泌
发表日期：2021
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