日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

P-1230. Tesamorelin (EGRIFTA WR and EGRIFTA®) Formulations: Bioequivalence in Healthy Participants

P-1230. Tesamorelin(EGRIFTA WR 和 EGRIFTA®)制剂:在健康受试者中的生物等效性

Denton, Stephen L; Lin, Mingqun; Nemeth, Elizabeta; Rikihisa, Yasuko; Caldji, Christian; Marsolais, Christian; Sicard, Eric; de Chantal, Marilyn; Anstett, Kaitlin

Safety, pharmacokinetics, and pharmacodynamics of MK-6194, an IL-2 mutein designed to selectively activate regulatory T cells: single ascending dose and multiple ascending dose trial data.

MK-6194(一种旨在选择性激活调节性 T 细胞的 IL-2 突变体)的安全性、药代动力学和药效学:单次递增剂量和多次递增剂量试验数据

Scheid Johannes F, Cunningham-Bussel Kiki, Kim Nancy, Agarwal Shiuli, Nieddu Garrett, Cote Josee, Lemoine Lieselotte, Decaesteker Tatjana, Mendez Luis, Paul Erina, Love-Gregory Latisha, Contreras Alejandra Virginia, Zhao Xuemei, Franco-Dilone Lucia, Pang Ling, Baltus Gretchen A, Beaumont Maribel, Shah Ketal, Higginson-Scott Nathan, Kis-Toth Katalin, Otipoby Kevin L, Viney Joanne L, Sicard Eric, Rottey Sylvie, Sundy John S, Van Dyck Kristien, Laethem Tine, Larson Patrick, Sutradhar Santosh, Wnek Richard, Bueters Tjerk, Lai Eseng, Stoch S Aubrey, Iwamoto Marian, Robbins Jonathan A

Licogliflozin for nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a study

利格列净治疗非酒精性脂肪性肝炎:一项随机、双盲、安慰剂对照的 2a 期研究

Harrison, Stephen A; Manghi, Federico Perez; Smith, William B; Alpenidze, Diana; Aizenberg, Diego; Klarenbeek, Naomi; Chen, Chi-Yi; Zuckerman, Eli; Ravussin, Eric; Charatcharoenwitthaya, Phunchai; Cheng, Pin-Nan; Katchman, Helena; Klein, Samuel; Ben-Ari, Ziv; Mendonza, Anisha E; Zhang, Yiming; Martic, Miljen; Ma, Shenglin; Kao, Sheena; Tanner, Sandra; Pachori, Alok; Badman, Michael K; He, YanLing; Ukomadu, Chinweike; Sicard, Eric

The safety and acceptability of twice-daily deferiprone for transfusional iron overload: A multicentre, open-label, phase 2 study

每日两次服用去铁酮治疗输血性铁过载的安全性和可接受性:一项多中心、开放标签的 II 期研究

Badawy, Sherif M; Kattamis, Antonis; Ezzat, Hatoon; Deschamps, Benoît; Sicard, Eric; Fradette, Caroline; Zhao, Feng; Tricta, Fernando; Chung Tsang, Yu; Sheth, Sujit; Piga, Antonio

The bioequivalence of fixed-dose combination tablets of bisoprolol and ramipril and its drug-drug interaction potential

比索洛尔和雷米普利固定剂量复方片剂的生物等效性及其药物相互作用潜力

Sus, Jan; Huguet, Jade; Bosak, Jan; Setnik, Beatrice; Hauser, Tomas; Sicard, Eric

Effects of common cold and concomitant administration of nasal decongestant on the pharmacokinetics and pharmacodynamics of nasal glucagon in otherwise healthy participants: A randomized clinical trial

普通感冒及同时使用鼻腔减充血剂对健康受试者鼻腔胰高血糖素药代动力学和药效学的影响:一项随机临床试验

Guzman, Cristina B; Dulude, Helene; Piché, Claude; Rufiange, Marianne; Sadoune, Aziz A; Rampakakis, Emmanouil; Carballo, Dolores; Triest, Myriam; Zhang, Michelle Xiaotian; Zhang, Shuyu; Tafreshi, Maryam; Sicard, Eric

The Effect of Food on Tramadol and Celecoxib Bioavailability Following Oral Administration of Co-Crystal of Tramadol-Celecoxib (CTC): A Randomised, Open-Label, Single-Dose, Crossover Study in Healthy Volunteers

食物对口服曲马多-塞来昔布共晶体(CTC)后曲马多和塞来昔布生物利用度的影响:一项在健康志愿者中进行的随机、开放标签、单剂量、交叉研究

Encina, Gregorio; Encabo, Mercedes; Escriche, Marisol; Lahjou, Mounia; Sicard, Eric; Smith, Kevin; Gascon, Neus; Plata-Salamán, Carlos; Videla, Sebastián

The Oral β-Lactamase SYN-004 (Ribaxamase) Degrades Ceftriaxone Excreted into the Intestine in Phase 2a Clinical Studies

口服β-内酰胺酶SYN-004(利巴沙酶)在2a期临床研究中可降解经肠道排泄的头孢曲松。

Kokai-Kun, John F; Roberts, Tracey; Coughlin, Olivia; Sicard, Eric; Rufiange, Marianne; Fedorak, Richard; Carter, Christian; Adams, Marijke H; Longstreth, James; Whalen, Heidi; Sliman, Joseph

Next-day residual effects of flibanserin on simulated driving performance in premenopausal women

氟班色林对绝经前女性模拟驾驶能力的次日残留效应

Kay, Gary G; Hochadel, Thomas; Sicard, Eric; Natarajan, Karthi K; Kim, Noel N

Single-Dose, Randomized, Open-Label, Two-Way, Crossover Bioequivalence Study of Two Formulations of Pregabalin 300 mg Hard Capsules in Healthy Volunteers Under Fasting Conditions

在健康志愿者空腹状态下,进行两种普瑞巴林300毫克硬胶囊制剂的单剂量、随机、开放标签、双向交叉生物等效性研究

Filipe, Augusto; Almeida, Susana; Pedroso, Pedro Filipe; Neves, Rita; Marques, Susana; Sicard, Eric; Massicotte, Julie; Ortuño, Jordi