日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A large-scale type I CBASS antiphage screen identifies the phage prohead protease as a key determinant of immune activation and evasion

大规模I型CBASS抗噬菌体筛选发现噬菌体前体蛋白酶是免疫激活和逃避的关键决定因素。

Desmond Richmond-Buccola ,Samuel J Hobbs ,Jasmine M Garcia ,Hunter Toyoda ,Jingjing Gao ,Sichen Shao ,Amy S Y Lee ,Philip J Kranzusch

The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center

eRF1降解剂SRI-41315在核糖体解码中心发挥分子胶的作用。

João P L Coelho # ,Matthew C J Yip # ,Keely Oltion ,Jack Taunton ,Sichen Shao

Mechanism of ASF1 Inhibition by CDAN1

CDAN1 抑制 ASF1 的机制

Samantha F Sedor, Sichen Shao

Cryo-EM structure of an active bacterial TIR-STING filament complex

活性细菌 TIR-STING 丝状复合物的低温电子显微镜结构

Benjamin R Morehouse, Matthew C J Yip, Alexander F A Keszei, Nora K McNamara-Bordewick, Sichen Shao, Philip J Kranzusch

ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins

ATP13A1 可防止折叠能力错误定位和错误定向的蛋白质发生 ERAD

Michael J McKenna, Benjamin M Adams, Vincent Chu, Joao A Paulo, Sichen Shao

Mechanism of client selection by the protein quality-control factor UBE2O

蛋白质质量控制因子 UBE2O 的客户选择机制

Matthew C J Yip #, Samantha F Sedor #, Sichen Shao

Didemnin B and ternatin-4 differentially inhibit conformational changes in eEF1A required for aminoacyl-tRNA accommodation into mammalian ribosomes

Didemnin B 和 ternatin-4 不同地抑制了氨酰基 tRNA 进入哺乳动物核糖体所需的 eEF1A 构象变化

Manuel F Juette #, Jordan D Carelli #, Emily J Rundlet #, Alan Brown, Sichen Shao, Angelica Ferguson, Michael R Wasserman, Mikael Holm, Jack Taunton, Scott C Blanchard

Cyclic CMP and cyclic UMP mediate bacterial immunity against phages

环状CMP和环状UMP介导细菌对噬菌体的免疫反应

Nitzan Tal ,Benjamin R Morehouse ,Adi Millman ,Avigail Stokar-Avihail ,Carmel Avraham ,Taya Fedorenko ,Erez Yirmiya ,Ehud Herbst ,Alexander Brandis ,Tevie Mehlman ,Yaara Oppenheimer-Shaanan ,Alexander F A Keszei ,Sichen Shao ,Gil Amitai ,Philip J Kranzusch ,Rotem Sorek

Structural insights into metazoan pretargeting GET complexes

对后生动物预定位GET复合物的结构洞察

Alexander F A Keszei, Matthew C J Yip, Ta-Chien Hsieh, Sichen Shao

Selective destabilization of polypeptides synthesized from NMD-targeted transcripts

NMD 靶向转录物合成多肽的选择性不稳定

Vincent Chu, Qing Feng, Yang Lim, Sichen Shao