Sickmier E Allen相关文献与解析，生知库 | 链接生命科学的每一步

Daniels, Matthew H; Castro, Jennifer; Lee, Young-Tae; Gotur, Deepali; Knockenhauer, Kevin E; Grigoriu, Simina; Lockbaum, Gordon J; Cheong, Jae Eun; Lu, Chuang; Brennan, David; Buker, Shane M; Liu, Julie; Yao, Shihua; Sparling, Brian A; Sickmier, E Allen; Ribich, Scott; Blakemore, Steve J; Silver, Serena J; Boriack-Sjodin, P Ann; Duncan, Kenneth W; Copeland, Robert A

DHX9

发表日期：2025

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Characterization of exoribonuclease XRN1 as a cancer target and identification of adenosine-3',5'-bisphosphate as a potent enzyme inhibitor.

核糖核酸外切酶 XRN1 作为癌症靶点的特性分析以及腺苷-3',5'-二磷酸作为强效酶抑制剂的鉴定

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-025-08005-y

Lockbaum Gordon J, Lynes Maureen M, Shen Sophie A, Liu Julie, Holt Nicholas, Nayak Sunaina P, Knockenhauer Kevin E, Yao Shihua, Sickmier E Allen, Raman Anugraha, Wu Jie, Case April, Shehaj Livia, Buker Shane M, Grigoriu Simina, Ribich Scott, Blakemore Stephen J, Sparling Brian A, Duncan Kenneth W, Copeland Robert A, Silver Serena J, Boriack-Sjodin P Ann

Crystal structures of the DExH-box RNA helicase DHX9

DExH盒RNA解旋酶DHX9的晶体结构

期刊:Acta Crystallographica Section D-Structural Biology

影响因子:3.8

doi:10.1107/S2059798323007611

Lee, Young Tae; Sickmier, E Allen; Grigoriu, Simina; Castro, Jennifer; Boriack-Sjodin, P Ann

DHX9

发表日期：2023

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Alternative conformations at the RNA-binding surface of the N-terminal U2AF(65) RNA recognition motif

N端U2AF(65) RNA识别基序的RNA结合表面的替代构象

期刊:Journal of Molecular Biology

影响因子:4.5

doi:10.1016/j.jmb.2006.11.077

Thickman, Karen R; Sickmier, E Allen; Kielkopf, Clara L

发表日期：2007

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Crystallization and preliminary X-ray analysis of a U2AF65 variant in complex with a polypyrimidine-tract analogue by use of protein engineering

利用蛋白质工程技术对U2AF65变体与多嘧啶序列类似物复合物进行结晶和初步X射线分析。

期刊:Acta Crystallographica Section F-Structural Biology and Crystallization Communications

影响因子:1.1

doi:10.1107/S1744309106012504

Sickmier, E Allen; Frato, Katherine E; Kielkopf, Clara L

发表日期：2006

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Discovery of ATX968: An Orally Available Allosteric Inhibitor of DHX9

ATX968 的发现：一种口服有效的 DHX9 变构抑制剂

Characterization of exoribonuclease XRN1 as a cancer target and identification of adenosine-3',5'-bisphosphate as a potent enzyme inhibitor.

核糖核酸外切酶 XRN1 作为癌症靶点的特性分析以及腺苷-3',5'-二磷酸作为强效酶抑制剂的鉴定

Crystal structures of the DExH-box RNA helicase DHX9

DExH盒RNA解旋酶DHX9的晶体结构

Alternative conformations at the RNA-binding surface of the N-terminal U2AF(65) RNA recognition motif

N端U2AF(65) RNA识别基序的RNA结合表面的替代构象

Crystallization and preliminary X-ray analysis of a U2AF65 variant in complex with a polypyrimidine-tract analogue by use of protein engineering

利用蛋白质工程技术对U2AF65变体与多嘧啶序列类似物复合物进行结晶和初步X射线分析。