日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

From General-Purpose to Disease-Specific Features: Aligning LLM Embeddings on a Disease-Specific Biomedical Knowledge Graph for Drug Repurposing

从通用特征到疾病特异性特征：将LLM嵌入对齐到疾病特异性生物医学知识图谱上以实现药物重定位

期刊:
影响因子:
doi:10.64898/2026.03.07.707871
Pandey, Suman; Talo, Muhammed; Siderovski, David P; Sumien, Nathalie; Bozdag, Serdar
发表日期：2026
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Functional Variation in RGS12 Should Not Preclude Methylphenidate Use in Bipolar Disorder with Established Mood Stabilization: Preclinical Evidence

RGS12功能变异不应妨碍在已取得情绪稳定的双相情感障碍患者中使用哌甲酯：临床前证据

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms262411993
Agogo-Mawuli, Percy S; Gross, Joshua D; Setola, Vincent; Gall, Bryan J; Siderovski, David P
RGS12
发表日期：2025
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The synthetic cannabinoid agonist WIN 55,212-2 reduces experimental pruritus via CB(2) receptor activation

合成大麻素激动剂WIN 55,212-2通过激活CB(2)受体减轻实验性瘙痒。

期刊:Neuropharmacology
影响因子:4.6
doi:10.1016/j.neuropharm.2024.110216
Reck, Antonio Matt; Siderovski, David P; Kinsey, Steven G
信号转导
发表日期：2025
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Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14

开发鸟苷三磷酸水解加速G蛋白信号调节因子-14活性的抑制剂

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2025.110611
Agogo-Mawuli, Percy S; Sadiya, Isra; Abramyan, Tigran M; Bosch, Dustin E; Emmitte, Kyle A; Colón-Pérez, Luis M; Kosloff, Mickey; Siderovski, David P
信号转导
发表日期：2025
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Developing inhibitors of the guanosine triphosphate hydrolysis accelerating activity of Regulator of G protein Signaling-14

开发鸟苷三磷酸水解加速G蛋白信号调节因子-14活性的抑制剂

期刊:
影响因子:
doi:10.1101/2025.06.11.659181
Agogo-Mawuli, Percy S; Sadiya, Isra; Abramyan, Tigran M; Bosch, Dustin E; Emmitte, Kyle A; Colon-Perez, Luis; Kosloff, Mickey; Siderovski, David P
信号转导
发表日期：2025
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Molecular Modeling and In Vitro Functional Analysis of the RGS12 PDZ Domain Variant Associated with High-Penetrance Familial Bipolar Disorder

与高外显率家族性双相情感障碍相关的RGS12 PDZ结构域变异体的分子建模和体外功能分析

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms252111431
Agogo-Mawuli, Percy S; Mendez, Joseph; Oestreich, Emily A; Bosch, Dustin E; Siderovski, David P
RGS12
发表日期：2024
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Self-activating G protein α subunits engage seven-transmembrane regulator of G protein signaling (RGS) proteins and a Rho guanine nucleotide exchange factor effector in the amoeba Naegleria fowleri

在福氏耐格里阿米巴中，自激活的G蛋白α亚基与七次跨膜G蛋白信号调节因子（RGS）蛋白和Rho鸟嘌呤核苷酸交换因子效应物相互作用。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2022.102167
Bosch, Dustin E; Jeck, William R; Siderovski, David P
信号转导
发表日期：2022
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Potential for Kappa-Opioid Receptor Agonists to Engineer Nonaddictive Analgesics: A Narrative Review

利用κ-阿片受体激动剂开发非成瘾性镇痛药的潜力：综述

期刊:Anesthesia and Analgesia
影响因子:3.8
doi:10.1213/ANE.0000000000005309
Kaski, Shane W; White, Allison N; Gross, Joshua D; Siderovski, David P
信号转导
发表日期：2021
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Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine

纳呋拉芬作为一种可减少阿片类药物用量的佐剂，通过增强靶向μ阿片受体激动剂吗啡的镇痛作用，进行临床前试验

期刊:Journal of Pharmacology and Experimental Therapeutics
影响因子:3.8
doi:10.1124/jpet.118.255661
Kaski, Shane W; White, Allison N; Gross, Joshua D; Trexler, Kristen R; Wix, Kim; Harland, Aubrie A; Prisinzano, Thomas E; Aubé, Jeffrey; Kinsey, Steven G; Kenakin, Terry; Siderovski, David P; Setola, Vincent
信号转导
发表日期：2019
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Single Nucleotide Polymorphisms in Chemosensory Pathway Genes GNB3, TAS2R19, and TAS2R38 Are Associated with Chronic Rhinosinusitis

化学感觉通路基因GNB3、TAS2R19和TAS2R38的单核苷酸多态性与慢性鼻窦炎相关

期刊:International Archives of Allergy and Immunology
影响因子:1.8
doi:10.1159/000499875
Purnell, Phillip R; Addicks, Benjamin L; Zalzal, Habib G; Shapiro, Scott; Wen, Sijin; Ramadan, Hassan H; Setola, Vincent; Siderovski, David P
信号转导
发表日期：2019
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