日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Patient-derived organoids and neurospheres recapitulate salient features of primary tumor heterogeneity

患者来源的类器官和神经球重现了原发肿瘤异质性的显著特征

Moore, Zachery; Storey, Claire; Brown, Daniel V; Valkovic, Adam; Spiteri, Montana; Pignatelli, Jasmine F; Oliver, Shannon J; Fakhri, Alana; Drummond, Katharine J; Hart, Jessica; Harris, Lachlan; Malinowski, Seth; Ligon, Keith L; Sieber, Oliver M; Whittle, James R; Freytag, Saskia; Best, Sarah A

SRP19 and the protein secretion machinery is a targetable vulnerability in cancers with APC loss.

SRP19 和蛋白质分泌机制是 APC 缺失的癌症中可靶向的脆弱点

Xi Xinqi, Liu Ling, Tuano Natasha, Tailhades Julien, Mouradov Dmitri, Steen Jason, Sieber Oliver, Cryle Max, Nguyen-Dumont Tu, Segelov Eva, Rosenbluh Joseph

Automated deep learning-based assessment of tumour-infiltrating lymphocyte density determines prognosis in colorectal cancer

基于深度学习的肿瘤浸润淋巴细胞密度自动评估可用于预测结直肠癌的预后

Millward, Joshua; He, Zhen; Nibali, Aiden; Mouradov, Dmitri; Mielke, Lisa A; Tran, Kelly; Chou, Angela; Hawkins, Nicholas J; Ward, Robyn L; Gill, Anthony J; Sieber, Oliver M; Williams, David S

Model systems and unique biological features of high and low-grade colorectal cancer (CRC) revealed by xenografting 84 human CRC cell lines.

通过对 84 种人类 CRC 细胞系进行异种移植,揭示了高低级别结直肠癌 (CRC) 的模型系统和独特的生物学特征

Luk Ian Y, Mooi Jennifer K, Mouradov Dmitri, Tan Tao, Scott Cameron M, Chionh Fiona, Jenkins Laura J, Reehorst Camilla M, Nightingale Rebecca, Savas Peter, Tse Janson Wt, Crake Rebekah Li, Batlle Eduard, Arango Diego, Dopeso Higino, Gibbs Peter, Tebbutt Niall C, Luwor Rod B, Scott Andrew M, Basheer Faiza, Dhillon Amardeep S, Clemons Nicholas J, Williams David S, Firestein Ron, Sieber Oliver M, Mariadason John M

Correction to: The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells

更正:抗癌药物APR-246可激活多种程序性细胞死亡过程以杀死恶性细胞。

Wang, Zilu; Hu, Huimin; Heitink, Luuk; Rogers, Kelly; You, Yue; Tan, Tao; Suen, Connie Li Wai; Garnham, Alex; Chen, Hao; Lieschke, Elizabeth; Diepstraten, Sarah T; Chang, Catherine; Chen, Tianwei; Moujalled, Diane; Sutherland, Kate; Lessene, Guillaume; Sieber, Oliver M; Visvader, Jane; Kelly, Gemma L; Strasser, Andreas

Author Correction: DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis

作者更正:DUSP5在CIMP高表达的结直肠癌中发生甲基化,但它并非肠道细胞增殖和肿瘤发生的主要调控因子。

Tögel, Lars; Nightingale, Rebecca; Wu, Rui; Chüeh, Anderly C; Al-Obaidi, Sheren; Luk, Ian; Dávalos-Salas, Mercedes; Chionh, Fiona; Murone, Carmel; Buchanan, Daniel D; Chatterton, Zac; Sieber, Oliver M; Arango, Diego; Tebbutt, Niall C; Williams, David; Dhillon, Amardeep S; Mariadason, John M

Evaluating Multiple Next-Generation Sequencing-Derived Tumor Features to Accurately Predict DNA Mismatch Repair Status

评估多种基于下一代测序的肿瘤特征以准确预测DNA错配修复状态

Walker, Romy; Georgeson, Peter; Mahmood, Khalid; Joo, Jihoon E; Makalic, Enes; Clendenning, Mark; Como, Julia; Preston, Susan; Joseland, Sharelle; Pope, Bernard J; Hutchinson, Ryan A; Kasem, Kais; Walsh, Michael D; Macrae, Finlay A; Win, Aung K; Hopper, John L; Mouradov, Dmitri; Gibbs, Peter; Sieber, Oliver M; O'Sullivan, Dylan E; Brenner, Darren R; Gallinger, Steven; Jenkins, Mark A; Rosty, Christophe; Winship, Ingrid M; Buchanan, Daniel D

Reprogrammed Lipid Metabolism and the Lipid-Associated Hallmarks of Colorectal Cancer

脂质代谢重编程与结直肠癌的脂质相关特征

Salita, Timothy; Rustam, Yepy H; Mouradov, Dmitri; Sieber, Oliver M; Reid, Gavin E

Beyond standard data collection - the promise and potential of BRAIN (Brain tumour Registry Australia INnovation and translation registry)

超越标准数据收集——BRAIN(澳大利亚脑肿瘤登记创新与转化登记)的前景和潜力

Gately, Lucy; Drummond, Katharine; Rosenthal, Mark; Harrup, Rosemary; Dowling, Anthony; Gogos, Andrew; Lwin, Zarnie; Collins, Ian; Campbell, David; Ahern, Elizabeth; Phillips, Claire; Gan, Hui K; Bennett, Iwan; Sieber, Oliver M; Gibbs, Peter

Evaluating the utility of tumour mutational signatures for identifying hereditary colorectal cancer and polyposis syndrome carriers

评估肿瘤突变特征在识别遗传性结直肠癌和息肉综合征携带者中的应用价值

Georgeson, Peter; Pope, Bernard J; Rosty, Christophe; Clendenning, Mark; Mahmood, Khalid; Joo, Jihoon E; Walker, Romy; Hutchinson, Ryan A; Preston, Susan; Como, Julia; Joseland, Sharelle; Win, Aung Ko; Macrae, Finlay A; Hopper, John L; Mouradov, Dmitri; Gibbs, Peter; Sieber, Oliver M; O'Sullivan, Dylan E; Brenner, Darren R; Gallinger, Steve; Jenkins, Mark A; Winship, Ingrid M; Buchanan, Daniel D