日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Reducing the Burden of Interaction Studies in Cancer Patients Using a Stable Isotopically Labeled Microtracer: A Proof-of-Concept Study with Alectinib

利用稳定同位素标记微示踪剂减轻癌症患者相互作用研究的负担：阿来替尼概念验证研究

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.70141
Mohmaed Ali, Ma Ida; van der Heijden, Lisa T; Tibben, Matthijs; Rosing, Hilde; Kalicharan, Raween; Ruiter, Gerrina; Beijnen, Jos H; Huisman-Siebinga, Hinke; Huitema, Alwin D R; Steeghs, Neeltje
肿瘤
肿瘤免疫
发表日期：2026
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Semi-Physiological Population Pharmacokinetic Modeling of Oral and Intravenous Paracetamol to Quantify Presystemic Metabolism and Enterohepatic Recirculation

口服和静脉注射对乙酰氨基酚的半生理群体药代动力学模型，用于量化首过代谢和肠肝循环

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.70168
Lau, Cedric; van Kesteren, Charlotte; Smeenk, Robert M; Beex-Oosterhuis, Marieke M; Koch, Birgit C P; Chan, Lingtak-Neander; Lin, Yvonne S; van Rongen, Anne; Knibbe, Catherijne A J; Huitema, Alwin D R; Huisman-Siebinga, Hinke
代谢
发表日期：2026
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Palbociclib exposure in relation to efficacy and toxicity in patients with advanced breast cancer

帕博西尼暴露量与晚期乳腺癌患者的疗效和毒性关系

期刊:ESMO Open
影响因子:8.3
doi:10.1016/j.esmoop.2025.104290
Buijs, S M; Mohmaed Ali, M I; Oomen-de Hoop, E; Braal, C L; Wortelboer, N; van Ommen-Nijhof, A; Sonke, G S; Konings, I R; Jager, A; Steeghs, N; Siebinga, H; Mathijssen, R H J; Huitema, A D R; Koolen, S L W
肿瘤
毒理研究
肿瘤免疫
乳腺癌
发表日期：2025
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A model of dyadic merging interactions explains human drivers' behavior from control inputs to decisions

二元融合交互模型解释了人类驾驶员从控制输入到决策的行为。

期刊:PNAS Nexus
影响因子:3.8
doi:10.1093/pnasnexus/pgae420
Siebinga, Olger; Zgonnikov, Arkady; Abbink, David A
发表日期：2024
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Quantification of biochemical PSA dynamics after radioligand therapy with [(177)Lu]Lu-PSMA-I&T using a population pharmacokinetic/pharmacodynamic model

利用群体药代动力学/药效动力学模型对放射性配体治疗后[(177)Lu]Lu-PSMA-I&T治疗后的生化PSA动态变化进行定量分析

期刊:Ejnmmi Physics
影响因子:3.2
doi:10.1186/s40658-024-00642-2
Siebinga, Hinke; de Wit-van der Veen, Berlinda J; de Vries-Huizing, Daphne M V; Vogel, Wouter V; Hendrikx, Jeroen J M A; Huitema, Alwin D R
PSA
发表日期：2024
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Predicting [(177)Lu]Lu-HA-DOTATATE kidney and tumor accumulation based on [(68)Ga]Ga-HA-DOTATATE diagnostic imaging using semi-physiological population pharmacokinetic modeling

利用半生理群体药代动力学模型，基于[(68)Ga]Ga-HA-DOTATATE诊断成像预测[(177)Lu]Lu-HA-DOTATATE在肾脏和肿瘤中的蓄积

期刊:Ejnmmi Physics
影响因子:3.2
doi:10.1186/s40658-023-00565-4
Siebinga, Hinke; de Wit-van der Veen, Berlinda J; Beijnen, Jos H; Stokkel, Marcel P M; Dorlo, Thomas P C; Huitema, Alwin D R; Hendrikx, Jeroen J M A
肿瘤
肿瘤免疫
发表日期：2023
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A physiologically based pharmacokinetic model for [(68)Ga]Ga-(HA-)DOTATATE to predict whole-body distribution and tumor sink effects in GEP-NET patients

基于生理的[(68)Ga]Ga-(HA-)DOTATATE药代动力学模型预测GEP-NET患者全身分布及肿瘤吸收效应

期刊:Ejnmmi Research
影响因子:3
doi:10.1186/s13550-023-00958-7
Siebinga, Hinke; de Wit-van der Veen, Berlinda J; Beijnen, Jos H; Dorlo, Thomas P C; Huitema, Alwin D R; Hendrikx, Jeroen J M A
肿瘤
肿瘤免疫
发表日期：2023
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Predicting the effect of different folate doses on [(68)Ga]Ga-PSMA-11 organ and tumor uptake using physiologically based pharmacokinetic modeling

利用基于生理的药代动力学模型预测不同叶酸剂量对[(68)Ga]Ga-PSMA-11在器官和肿瘤中的摄取的影响

期刊:Ejnmmi Research
影响因子:3
doi:10.1186/s13550-023-01008-y
Siebinga, Hinke; Hendrikx, Jeroen J M A; Huitema, Alwin D R; de Wit-van der Veen, Berlinda J
肿瘤
肿瘤免疫
发表日期：2023
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Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of (177) Lu-PSMA-617 in prostate cancer patients

利用影像数据建立群体药代动力学剂量模型，评估前列腺癌患者体内 (177)Lu-PSMA-617 药代动力学的变异性

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.12914
Siebinga, Hinke; Privé, Bastiaan M; Peters, Steffie M B; Nagarajah, James; Dorlo, Thomas P C; Huitema, Alwin D R; de Wit-van der Veen, Berlinda J; Hendrikx, Jeroen J M A
肿瘤
前列腺癌
肿瘤免疫
发表日期：2023
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The impact of a summative national prescribing assessment and curriculum type on the development of the prescribing competence of junior doctors

全国性处方能力评估及课程类型对初级医生处方能力发展的影响

期刊:European Journal of Clinical Pharmacology
影响因子:2.7
doi:10.1007/s00228-023-03567-4
Donker, Erik M; Osmani, Hayaudin; Brinkman, David J; van Rosse, Floor; Janssen, Ben; Knol, Wilma; Dumont, Glenn; Jorens, Philippe G; Dupont, Alain; Christiaens, Thierry; van Smeden, Jeroen; de Waard-Siebinga, Itte; Peeters, Laura E J; Goorden, Ronald; Hessel, Marleen; Lissenberg-Witte, Birgit I; Richir, Milan C; van Agtmael, Michiel A; Kramers, Cornelis; Tichelaar, Jelle
发表日期：2023
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