Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia
可溶性α-突触核蛋白-抗体复合物激活hiPSC衍生小胶质细胞中的NLRP3炎症小体
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2025847118
Trudler, Dorit; Nazor, Kristopher L; Eisele, Yvonne S; Grabauskas, Titas; Dolatabadi, Nima; Parker, James; Sultan, Abdullah; Zhong, Zhenyu; Goodwin, Marshall S; Levites, Yona; Golde, Todd E; Kelly, Jeffery W; Sierks, Michael R; Schork, Nicholas J; Karin, Michael; Ambasudhan, Rajesh; Lipton, Stuart A
胶质细胞
炎症
炎性小体
炎症/感染
神经科学
LRP3
NLRP3
细胞生物学
炎性小体
免疫/内分泌