日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Pyrazole derivatives as selective orexin-2 receptor antagonists (2-SORA): synthesis, structure-activity-relationship, and sleep-promoting properties in rats

吡唑衍生物作为选择性食欲素-2受体拮抗剂（2-SORA）：合成、构效关系及在大鼠中的促睡眠特性

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d3md00573a
Brotschi, Christine; Bolli, Martin H; Gatfield, John; Roch, Catherine; Sifferlen, Thierry; Treiber, Alexander; Williams, Jodi T; Boss, Christoph
信号转导
Rat
发表日期：2024
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Phase IB Study of GITR Agonist Antibody TRX518 Singly and in Combination with Gemcitabine, Pembrolizumab, or Nivolumab in Patients with Advanced Solid Tumors

GITR激动剂抗体TRX518单药及联合吉西他滨、帕博利珠单抗或纳武利尤单抗治疗晚期实体瘤患者的IB期研究

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-22-0339
Davar, Diwakar; Zappasodi, Roberta; Wang, Hong; Naik, Girish S; Sato, Takami; Bauer, Todd; Bajor, David; Rixe, Olivier; Newman, Walter; Qi, Jingjing; Holland, Aliya; Wong, Phillip; Sifferlen, Lianna; Piper, Diane; Sirard, Cynthia A; Merghoub, Taha; Wolchok, Jedd D; Luke, Jason J
TRX
发表日期：2022
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Structure-activity relationship, biological, and pharmacological characterization of the proline sulfonamide ACT-462206: a potent, brain-penetrant dual orexin 1/orexin 2 receptor antagonist

脯氨酰磺酰胺 ACT-462206 的构效关系、生物学和药理学表征：一种强效的脑渗透性双食欲素 1/食欲素 2 受体拮抗剂

期刊:ChemMedChem
影响因子:3.6
doi:10.1002/cmdc.201402258
Christoph Boss, Catherine Roch-Brisbare, Michel A Steiner, Alexander Treiber, Hendrik Dietrich, Francois Jenck, Markus von Raumer, Thierry Sifferlen, Christine Brotschi, Bibia Heidmann, Jodi T Williams, Hamed Aissaoui, Romain Siegrist, John Gatfield
信号转导
发表日期：2014
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