日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pro-Oxidant Auranofin and Glutathione-Depleting Combination Unveils Synergistic Lethality in Glioblastoma Cells with Aberrant Epidermal Growth Factor Receptor Expression

促氧化剂金诺芬和谷胱甘肽耗竭剂的组合揭示了在具有异常表皮生长因子受体表达的胶质母细胞瘤细胞中的协同杀伤力

Elvis Martinez-Jaramillo, Fatemeh Jamali, Farah H Abdalbari, Bassam Abdulkarim, Bertrand J Jean-Claude, Carlos M Telleria, Siham Sabri

Auranofin Induces Lethality Driven by Reactive Oxygen Species in High-Grade Serous Ovarian Cancer Cells

金诺芬在高级别浆液性卵巢癌细胞中诱导活性氧驱动的致死率

Farah H Abdalbari, Elvis Martinez-Jaramillo, Benjamin N Forgie, Estelle Tran, Edith Zorychta, Alicia A Goyeneche, Siham Sabri, Carlos M Telleria

An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy

通过 PKR 进行的综合应激反应可抑制 HER2+ 癌症并改善曲妥珠单抗治疗

Cedric Darini, Nour Ghaddar, Catherine Chabot, Gloria Assaker, Siham Sabri, Shuo Wang, Jothilatha Krishnamoorthy, Marguerite Buchanan, Adriana Aguilar-Mahecha, Bassam Abdulkarim, Jean Deschenes, Jose Torres, Josie Ursini-Siegel, Mark Basik, Antonis E Koromilas

PTHrP, A Biomarker for CNS Metastasis in Triple-Negative Breast Cancer and Selection for Adjuvant Chemotherapy in Node-Negative Disease

PTHrP,一种用于三阴性乳腺癌中枢神经系统转移的生物标志物,以及用于淋巴结阴性疾病辅助化疗的选择。

Gloria Assaker ,Anne Camirand ,Bassam Abdulkarim ,Atilla Omeroglu ,Jean Deschenes ,Kurian Joseph ,Abu Shadat Mohammod Noman ,Agnihotram V Ramana Kumar ,Richard Kremer ,Siham Sabri

CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide

CUX1 刺激 APE1 酶活性并增强胶质母细胞瘤细胞对单烷化剂替莫唑胺的抵抗力

Simran Kaur, Zubaidah M Ramdzan, Marie-Christine Guiot, Li Li, Lam Leduy, Dindial Ramotar, Siham Sabri, Bassam Abdulkarim, Alain Nepveu

Cleavage of the extracellular domain of junctional adhesion molecule-A is associated with resistance to anti-HER2 therapies in breast cancer settings

连接粘附分子-A 胞外域的裂解与乳腺癌环境中对抗 HER2 疗法的耐药性有关

Astrid O Leech, Sri HariKrishna Vellanki, Emily J Rutherford, Aoife Keogh, Hanne Jahns, Lance Hudson, Norma O'Donovan, Siham Sabri, Bassam Abdulkarim, Katherine M Sheehan, Elaine W Kay, Leonie S Young, Arnold D K Hill, Yvonne E Smith, Ann M Hopkins

High Myc expression and transcription activity underlies intra-tumoral heterogeneity in triple-negative breast cancer

高 Myc 表达和转录活性是三阴性乳腺癌肿瘤内异质性的基础

Nidhi Gupta, Karen Jung, Chengsheng Wu, Abdulraheem Alshareef, Hind Alqahtani, Sambasivarao Damaraju, John R Mackey, Sunita Ghosh, Siham Sabri, Bassam S Abdulkarim, Gilbert Bigras, Raymond Lai

Response to stereotactic ablative radiotherapy in a novel orthotopic model of non-small cell lung cancer

非小细胞肺癌新型原位模型对立体定向消融放射治疗的反应

Ayman Oweida, Siham Sabri, Areej Al-Rabea, Mojgan Ebrahimi, Russel Ruo, Richard Fraser, Jan Seuntjens, Bassam Abdulkarim

Differential response to ablative ionizing radiation in genetically distinct non-small cell lung cancer cells

基因上不同的非小细胞肺癌细胞对烧蚀电离辐射的不同反应

Ayman Oweida, Zeinab Sharifi, Hani Halabi, Yaoxian Xu, Siham Sabri, Bassam Abdulkarim

Sensitivity to PRIMA-1MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status

对 PRIMA-1MET 的敏感性与人类胶质母细胞瘤细胞和胶质母细胞瘤干细胞中 MGMT 降低有关,与 p53 状态无关

Mariia Patyka, Zeinab Sharifi, Kevin Petrecca, Jose Mansure, Bertrand Jean-Claude, Siham Sabri