Sikandar Azam相关文献与解析，生知库 | 链接生命科学的每一步

Mays Mohammed Salih ，Chi G Weindel ，Eric Malekos ，Lisa Sudek ，Sol Katzman ，Cory J Mabry ，Morgan J Chapman ，Aja K Coleman ，Sikandar Azam ，Robert O Watson ，Kristin L Patrick ，Susan Carpenter

巨噬细胞

免疫/内分泌

细胞生物学

发表日期：2025

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The early macrophage response to pathogens requires dynamic regulation of the nuclear paraspeckle

巨噬细胞对病原体的早期反应需要核副啄木鸟的动态调节

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.2312587121

Sikandar Azam, Kaitlyn S Armijo, Chi G Weindel, Morgan J Chapman, Alice Devigne, Shinichi Nakagawa, Tetsuro Hirose, Susan Carpenter, Robert O Watson, Kristin L Patrick

Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis

线粒体活性氧通过gasdermin D介导的坏死性凋亡促进细胞对感染的易感性

期刊:Cell

影响因子:45.5

doi:10.1016/j.cell.2022.06.038

Chi G Weindel ，Eduardo L Martinez ，Xiao Zhao ，Cory J Mabry ，Samantha L Bell ，Krystal J Vail ，Aja K Coleman ，Jordyn J VanPortfliet ，Baoyu Zhao ，Allison R Wagner ，Sikandar Azam ，Haley M Scott ，Pingwei Li ，A Phillip West ，Jason Karpac ，Kristin L Patrick ，Robert O Watson

Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway

SRSF1 和 SRSF7 序列依赖性募集至无内含子的 lncRNA NKILA，通过 TREX/TAP 通路促进核输出

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkab445

Misbah Khan, Shuai Hou, Sikandar Azam, Haixin Lei

其它

发表日期：2021

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XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence

XAB2 缺失导致 POLR2A 内含子滞留，从而损害整体转录并促进细胞衰老。

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkz532

Shuai Hou ，Dajun Qu ，Yue Li ，Baohui Zhu ，Dapeng Liang ，Xinyue Wei ，Wei Tang ，Qian Zhang ，Jiaojiao Hao ，Wei Guo ，Weijie Wang ，Siqi Zhao ，Qi Wang ，Sikandar Azam ，Misbah Khan ，Haidong Zhao ，Liye Zhang ，Haixin Lei

Nuclear retention element recruits U1 snRNP components to restrain spliced lncRNAs in the nucleus

核保留元件募集 U1 snRNP 成分来抑制细胞核内剪接的 lncRNA

期刊:RNA Biology

影响因子:3.6

doi:10.1080/15476286.2019.1620061

Sikandar Azam, Shuai Hou, Baohui Zhu, Weijie Wang, Tian Hao, Xiangxue Bu, Misbah Khan, Haixin Lei

XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE

XAB2通过转录调控CENPE在有丝分裂细胞周期进程中发挥作用

期刊:Cell Death & Disease

影响因子:8.1

doi:10.1038/cddis.2016.313

Shuai Hou, Na Li, Qian Zhang, Hui Li, Xinyue Wei, Tian Hao, Yue Li, Sikandar Azam, Caigang Liu, Wei Cheng, Bilian Jin, Quentin Liu, Man Li, Haixin Lei

HuR antagonizes the effect of an intronic pyrimidine-rich sequence in regulating WT1 +/-KTS isoforms

HuR 拮抗内含子嘧啶富集序列在调节 WT1 +/-KTS 亚型中的作用

期刊:RNA Biology

影响因子:3.6

doi:10.1080/15476286.2015.1102831

Hui Li, Shuai Hou, Tian Hao, Sikandar Azam, Caigang Liu, Lei Shi, Haixin Lei

信号转导

发表日期：2015

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Myeloid-specific HNRNPA2B1 deficiency disrupts macrophage function and in vivo responses

髓系特异性HNRNPA2B1缺陷会破坏巨噬细胞功能和体内反应。

The early macrophage response to pathogens requires dynamic regulation of the nuclear paraspeckle

巨噬细胞对病原体的早期反应需要核副啄木鸟的动态调节

Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis

线粒体活性氧通过gasdermin D介导的坏死性凋亡促进细胞对感染的易感性

Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway

SRSF1 和 SRSF7 序列依赖性募集至无内含子的 lncRNA NKILA，通过 TREX/TAP 通路促进核输出

XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence

XAB2 缺失导致 POLR2A 内含子滞留，从而损害整体转录并促进细胞衰老。

Nuclear retention element recruits U1 snRNP components to restrain spliced lncRNAs in the nucleus

核保留元件募集 U1 snRNP 成分来抑制细胞核内剪接的 lncRNA

XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE

XAB2通过转录调控CENPE在有丝分裂细胞周期进程中发挥作用

HuR antagonizes the effect of an intronic pyrimidine-rich sequence in regulating WT1 +/-KTS isoforms

HuR 拮抗内含子嘧啶富集序列在调节 WT1 +/-KTS 亚型中的作用