日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A randomized, double-blind, placebo-controlled, Phase 1 study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of an immediate-release oral ketamine capsule in healthy volunteers

一项随机、双盲、安慰剂对照的 I 期研究,旨在调查速释口服氯胺酮胶囊在健康志愿者中的安全性、耐受性、药代动力学和药效学。

Qureshi, Mutahira; Silman, Daniel; Gadelrab, Romayne; Stein, Hans-Christian; Carmellini, Pietro; Duncan, Graeme; Mehta, Mitul A; Young, Allan H; Reilly, Carmel; Juruena, Mario F

Longitudinal validation of the Maudsley 3-item visual analogue scale (M3VAS): a new, brief, patient-reported outcome measure of depression

Maudsley 3项视觉模拟量表(M3VAS)的纵向验证:一种新的、简短的、患者自评的抑郁症结局测量工具

Silman, Daniel; Middag, Maria Elena; Cleare, Anthony J; Young, Allan H; Strawbridge, Rebecca

A randomised controlled trial to evaluate the clinical and cost-effectiveness of Stimulant compared with Non-stimulant medication for adults with Attention-deficit/hyperactivity disorder and a history of Psychosis or biPolar disordER: SNAPPER

一项随机对照试验,旨在评估兴奋剂类药物与非兴奋剂类药物在治疗患有注意力缺陷/多动障碍且有精神病或双相情感障碍病史的成年患者方面的临床疗效和成本效益。

Loi, Shrushma; Joshee, Paras; Ottridge, Ryan; Woolley, Rebecca; Gkini, Eleni; Asherson, Philip; Young, Allan H; Al-Janabi, Hareth; Broome, Matthew; Roberts, Anya; Gottlieb, Natalie; Hindmarch, Paul; Silman, Daniel; Sharma, Paritosh; Juruena, Mario; Nair, Rajesh; Mukherjee, Tirthankar; Katshu, Mohammad Zia Ul Haq; Marwaha, Steven

Phase I/IIa study to assess the safety, immunogenicity and efficacy of ChAdOx1-MVA vectored vaccines expressing a novel liver-stage malaria dual antigen LS2 by sporozoite challenge in malaria-naïve adults

一项 I/IIa 期研究旨在评估 ChAdOx1-MVA 载体疫苗(表达一种新型肝期疟疾双抗原 LS2)在未感染过疟疾的成年人中通过孢子攻击的安全性、免疫原性和有效性。

Silman, Daniel; Flaxman, Amy; Datoo, Mehreen; Edwards, Nick J; Ramos-Lopez, Fernando; Mitton, Celia; Mair, Catherine; Bellamy, Duncan; Bowyer, Georgina; Morter, Richard; Halbroth, Benedict; Venkatraman, Navin; Folegatti, Pedro M; Marshall, Julia; Poulton, Ian; Bajer, Amelia; Salman, Ahmed M; Berrie, Eleanor; Baum, Jake; Blagborough, Andrew M; Crocker, Wendy; Roberts, Rachel; Lawrie, Alison M; Spencer, Alexandra J; Gilbert, Sarah C; Ewer, Katie J; Hill, Adrian V S

Clozapine and Sweet's syndrome: case report

氯氮平与斯威特综合征:病例报告

Bunting, Apphia; Silman, Daniel; Karia, Minesh; Johnson, Sophie

Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial.

中东呼吸综合征冠状病毒病毒载体候选疫苗的安全性和免疫原性:剂量递增、开放标签、非随机、非对照的 1 期试验

Folegatti Pedro M, Bittaye Mustapha, Flaxman Amy, Lopez Fernando Ramos, Bellamy Duncan, Kupke Alexandra, Mair Catherine, Makinson Rebecca, Sheridan Jonathan, Rohde Cornelius, Halwe Sandro, Jeong Yuji, Park Young-Shin, Kim Jae-Ouk, Song Manki, Boyd Amy, Tran Nguyen, Silman Daniel, Poulton Ian, Datoo Mehreen, Marshall Julia, Themistocleous Yrene, Lawrie Alison, Roberts Rachel, Berrie Eleanor, Becker Stephan, Lambe Teresa, Hill Adrian, Ewer Katie, Gilbert Sarah