日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Vitamin A is necessary for acquisition, but not for expression or progression, of CNS autoimmunity

维生素A是中枢神经系统自身免疫性疾病发生所必需的,但并非其表达或进展所必需的。

Horai, Reiko; Zhou, Ru; Bing, So Jin; Wloka, Kaska; Jittyasothorn, Yingyos; Duncan, Todd E; Mattapallil, Mary J; Silver, Phyllis B; Chan, Chi-Chao; Caspi, Rachel R

Mincle Activation and the Syk/Card9 Signaling Axis Are Central to the Development of Autoimmune Disease of the Eye

Mincle激活和Syk/Card9信号通路在眼部自身免疫性疾病的发生发展中起着核心作用

Lee, Ellen J; Brown, Brieanna R; Vance, Emily E; Snow, Paige E; Silver, Phyllis B; Heinrichs, David; Lin, Xin; Iwakura, Yoichiro; Wells, Christine A; Caspi, Rachel R; Rosenzweig, Holly L

Microbiota-Dependent Activation of an Autoreactive T Cell Receptor Provokes Autoimmunity in an Immunologically Privileged Site

微生物群依赖性自身反应性T细胞受体激活可诱发免疫豁免部位的自身免疫。

Horai, Reiko; Zárate-Bladés, Carlos R; Dillenburg-Pilla, Patricia; Chen, Jun; Kielczewski, Jennifer L; Silver, Phyllis B; Jittayasothorn, Yingyos; Chan, Chi-Chao; Yamane, Hidehiro; Honda, Kenya; Caspi, Rachel R

NK-DC crosstalk controls the autopathogenic Th17 response through an innate IFN-γ-IL-27 axis

NK细胞与树突状细胞(DC)之间的相互作用通过固有IFN-γ-IL-27轴调控自身致病性Th17反应。

Chong, Wai Po; van Panhuys, Nicholas; Chen, Jun; Silver, Phyllis B; Jittayasothorn, Yingyos; Mattapallil, Mary J; Germain, Ronald N; Caspi, Rachel R

Breakdown of immune privilege and spontaneous autoimmunity in mice expressing a transgenic T cell receptor specific for a retinal autoantigen

表达针对视网膜自身抗原的转基因T细胞受体的小鼠出现免疫豁免破坏和自发性自身免疫

Horai, Reiko; Silver, Phyllis B; Chen, Jun; Agarwal, Rajeev K; Chong, Wai Po; Jittayasothorn, Yingyos; Mattapallil, Mary J; Nguyen, Sonia; Natarajan, Kannan; Villasmil, Rafael; Wang, Peng; Karabekian, Zaruhi; Lytton, Simon D; Chan, Chi-Chao; Caspi, Rachel R

The living eye "disarms" uncommitted autoreactive T cells by converting them to Foxp3(+) regulatory cells following local antigen recognition

活体眼球在识别局部抗原后,通过将未分化的自身反应性T细胞转化为Foxp3(+)调节性细胞来“解除”这些T细胞的武装。

Zhou, Ru; Horai, Reiko; Silver, Phyllis B; Mattapallil, Mary J; Zárate-Bladés, Carlos R; Chong, Wai Po; Chen, Jun; Rigden, Rachael C; Villasmil, Rafael; Caspi, Rachel R

Rodent models of experimental autoimmune uveitis

啮齿动物实验性自身免疫性葡萄膜炎模型

Agarwal, Rajeev K; Silver, Phyllis B; Caspi, Rachel R

Inhibition of experimental auto-immune uveitis by the A3 adenosine receptor agonist CF101

A3腺苷受体激动剂CF101对实验性自身免疫性葡萄膜炎的抑制作用

Bar-Yehuda, Sara; Luger, Dror; Ochaion, Avivit; Cohen, Shira; Patokaa, Renana; Zozulya, Galina; Silver, Phyllis B; de Morales, Jose Maria Garcia Ruiz; Caspi, Rachel R; Fishman, Pnina

Calcitriol suppresses antiretinal autoimmunity through inhibitory effects on the Th17 effector response.

骨化三醇通过抑制 Th17 效应反应来抑制抗视网膜自身免疫

Tang Jun, Zhou Ru, Luger Dror, Zhu Wei, Silver Phyllis B, Grajewski Rafael S, Su Shao-Bo, Chan Chi-Chao, Adorini Luciano, Caspi Rachel R

Repertoire analysis and new pathogenic epitopes of IRBP in C57BL/6 (H-2b) and B10.RIII (H-2r) mice

C57BL/6 (H-2b) 和 B10.RIII (H-2r) 小鼠 IRBP 的谱系分析及新的致病表位

Cortes, Lizette M; Mattapallil, Mary J; Silver, Phyllis B; Donoso, Larry A; Liou, Gregory I; Zhu, Wei; Chan, Chi-Chao; Caspi, Rachel R