日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

rVSVΔG-ZEBOV-GP Vaccine Is Highly Immunogenic and Efficacious Across a Wide Dose Range in a Nonhuman Primate EBOV Challenge Model

在非人灵长类动物埃博拉病毒攻击模型中,rVSVΔG-ZEBOV-GP疫苗在较宽的剂量范围内均具有高度免疫原性和有效性。

Shurtleff, Amy C; Trefry, John C; Dubey, Sheri; Sunay, Melek M E; Liu, Kenneth; Chen, Ziqiang; Eichberg, Michael; Silvera, Peter M; Kwilas, Steve A; Hooper, Jay W; Martin, Shannon; Simon, Jakub K; Coller, Beth-Ann G; Monath, Thomas P

Treatment with the smallpox antiviral tecovirimat (ST-246) alone or in combination with ACAM2000 vaccination is effective as a postsymptomatic therapy for monkeypox virus infection

单独使用天花抗病毒药物替考韦瑞特(ST-246)或联合ACAM2000疫苗治疗,可有效作为猴痘病毒感染的症状后治疗方法。

Berhanu, Aklile; Prigge, Jonathan T; Silvera, Peter M; Honeychurch, Kady M; Hruby, Dennis E; Grosenbach, Douglas W

Smallpox vaccine with integrated IL-15 demonstrates enhanced in vivo viral clearance in immunodeficient mice and confers long term protection against a lethal monkeypox challenge in cynomolgus monkeys.

含有整合 IL-15 的天花疫苗在免疫缺陷小鼠体内表现出增强的病毒清除能力,并能为食蟹猴提供针对致命性猴痘攻击的长期保护

Zielinski Rafal J, Smedley Jeremy V, Perera Pin-Yu, Silvera Peter M, Waldmann Thomas A, Capala Jacek, Perera Liyanage P