Mutations of six amino acid residues in a B domain-deleted blood coagulation factor VIII have a cumulative effect on increasing its secretion.
缺失 B 结构域的血液凝固因子 VIII 中六个氨基酸残基的突变会累积性地增加其分泌。
期刊:Research and Practice in Thrombosis and Haemostasis
影响因子:3.4
doi:10.1016/j.rpth.2025.103325
Shi Bo, Olivares Philip, Parunov Leonid A, Liang Yideng, Chun Haarin, Wu Wells W, Simhadri Vijaya L, Bajgain Pratima, Jankowski Wojciech, Krivega Margarita, Poniatowski Julia, Del Greco Elizabeth, Krivega Ivan, Shestopal Svetlana A, Zulfiker Abu Hasanat Md, Sauna Zuben E, Sarafanov Andrey G
