日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Exploring the Li(+) transporting mutant of NCX_Mj for assigning ion binding sites of mitochondrial NCLX

探索 NCX_Mj 的 Li(+) 转运突变体，以确定线粒体 NCLX 的离子结合位点

期刊:Cell Calcium
影响因子:4
doi:10.1016/j.ceca.2022.102651
Giladi, Moshe; Mitra, Sunayana; Simhaev, Luba; Hiller, Reuben; Refaeli, Bosmat; Strauss, Tali; Baiz, Carlos R; Khananshvili, Daniel
线粒体
发表日期：2022
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Allosteric inhibitors targeting the calmodulin-PIP2 interface of SK4 K+ channels for atrial fibrillation treatment

针对 SK4 K+ 通道钙调蛋白-PIP2 界面的变构抑制剂用于房颤治疗

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:
doi:10.1073/pnas.2202926119
Shira Burg, Shir Shapiro, Asher Peretz, Elvira Haimov, Boris Redko, Adva Yeheskel, Luba Simhaev, Hamutal Engel, Avi Raveh, Ariel Ben-Bassat, Michael Murninkas, Rotem Polak, Yoni Haitin, Yoram Etzion, Bernard Attali
信号转导
TRPA1
发表日期：2022
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The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue

CFTR P67L 变体揭示了 N 端套索螺旋在通道折叠、成熟和药物拯救中的关键作用

期刊:Journal of Biological Chemistry
影响因子:4
doi:10.1016/j.jbc.2021.100598
Carleen Mae Sabusap, Disha Joshi, Luba Simhaev, Kathryn E Oliver, Hanoch Senderowitz, Marcel van Willigen, Ineke Braakman, Andras Rab, Eric J Sorscher, Jeong S Hong
CFTR
发表日期：2021
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A unique mechanism of inactivation gating of the Kv channel family member Kv7.1 and its modulation by PIP2 and calmodulin

Kv通道家族成员Kv7.1独特的失活门控机制及其受PIP2和钙调蛋白的调节

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.abd6922
Lipinsky, Maya; Tobelaim, William Sam; Peretz, Asher; Simhaev, Luba; Yeheskel, Adva; Yakubovich, Daniel; Lebel, Guy; Paas, Yoav; Hirsch, Joel A; Attali, Bernard
发表日期：2020
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A novel specific PERK activator reduces toxicity and extends survival in Huntington's disease models

一种新型特异性PERK激活剂可降低亨廷顿病模型的毒性并延长生存期。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-020-63899-4
Ganz, Javier; Shacham, Talya; Kramer, Maria; Shenkman, Marina; Eiger, Hagit; Weinberg, Nitai; Iancovici, Ori; Roy, Somnath; Simhaev, Luba; Da'adoosh, Benny; Engel, Hamutal; Perets, Nisim; Barhum, Yael; Portnoy, Moshe; Offen, Daniel; Lederkremer, Gerardo Z
毒理研究
PERK
MAPK/ERK
发表日期：2020
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An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters

古老的 CFTR 直系同源物为 ABC 转运蛋白的分子进化提供信息

期刊:Developmental Cell
影响因子:10.7
doi:10.1016/j.devcel.2019.09.017
Guiying Cui, Jeong Hong, Yu-Wen Chung-Davidson, Daniel Infield, Xin Xu, Jindong Li, Luba Simhaev, Netaly Khazanov, Brandon Stauffer, Barry Imhoff, Kirsten Cottrill, J Edwin Blalock, Weiming Li, Hanoch Senderowitz, Eric Sorscher, Nael A McCarty, Amit Gaggar
信号转导
发表日期：2019
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