Siming Zhao相关文献与解析，生知库 | 链接生命科学的每一步

Efficacy and Safety of Biosimilar QL1207 vs. the Reference Aflibercept for Patients with Neovascular Age-Related Macular Degeneration: A Randomized Phase 3 Trial

生物类似药QL1207与参考药物阿柏西普治疗新生血管性年龄相关性黄斑变性的疗效和安全性：一项随机3期试验

Li, Bing; Fan, Ke; Zhang, Tonghe; Wu, Zhifeng; Zeng, Siming; Zhao, Mingwei; Ren, Qian; Zheng, Dongping; Wang, Lifei; Liu, Xiaoling; Han, Mei; Song, Yanping; Ye, Jian; Pei, Cheng; Yi, Jinglin; Wang, Xian; Peng, Hui; Zhang, Hong; Zhou, Zhanyu; Liang, Xiaoling; Yu, Fangliang; Wu, Miaoqin; Li, Chaopeng; Lei, Chunling; Hao, Jilong; Tang, Luosheng; Yuan, Huiping; Cai, Shanjun; Li, Qiuming; Zhong, Jingxiang; Li, Suyan; Liu, Lin; Ke, Min; Wang, Jing; Wang, Hui; Zhu, Mengli; Wang, Zenghua; Yan, Yang; Wang, Feng; Chen, Youxin

发表日期：2024

文献求助收藏

Baicalein-A Potent Pro-Homeostatic Regulator of Microglia in Retinal Ischemic Injury

黄芩苷——视网膜缺血损伤中小胶质细胞的强效促稳态调节剂

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2022.837497

Li Pan ，Ying Hon Sze ，Menglu Yang ，Jing Tang ，Siming Zhao ，Irvin Yi ，Chi-Ho To ，Chuen Lam ，Dong Feng Chen ，Kin-Sang Cho ，Chi-Wai Do

Oral Administration of Branched-Chain Amino Acids Attenuates Atherosclerosis by Inhibiting the Inflammatory Response and Regulating the Gut Microbiota in ApoE-Deficient Mice

口服支链氨基酸可通过抑制炎症反应和调节肠道菌群来减轻ApoE缺陷小鼠的动脉粥样硬化

期刊:Nutrients

影响因子:5

doi:10.3390/nu14235065

Li, Ziyun; Zhang, Ranran; Mu, Hongna; Zhang, Wenduo; Zeng, Jie; Li, Hongxia; Wang, Siming; Zhao, Xianghui; Chen, Wenxiang; Dong, Jun; Yang, Ruiyue

Novel Insights Into the Sulfated Glucuronic Acid-Based Anti-SARS-CoV-2 Mechanism of Exopolysaccharides From Halophilic Archaeon Haloarcula hispanica

嗜盐古菌西班牙盐弧菌胞外多糖中硫酸葡萄糖醛酸抗SARS-CoV-2机制的新见解

期刊:Frontiers in Chemistry

影响因子:4.2

doi:10.3389/fchem.2022.871509

Xu, Yueqiang; Li, Yan; You, Xin; Pei, Caixia; Wang, Zhuo; Jiao, Siming; Zhao, Xin; Lin, Xuan; Lü, Yang; Jin, Cheng; Gao, George Fu; Li, Jianjun; Wang, Qi; Du, Yuguang

SARS-CoV-2

发表日期：2022

文献求助收藏

Detailed modeling of positive selection improves detection of cancer driver genes

正向选择的详细建模可提高癌症驱动基因的检测率

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-019-11284-9

Siming Zhao, Jun Liu, Pranav Nanga, Yuwen Liu, A Ercument Cicek, Nicholas Knoblauch, Chuan He, Matthew Stephens, Xin He

肿瘤

发表日期：2019

文献求助收藏

Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy

宫颈癌全外显子组测序确定激活 ERBB2 和 PIK3CA 突变作为联合治疗的靶点

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.1911385116

Luca Zammataro, Salvatore Lopez, Stefania Bellone, Francesca Pettinella, Elena Bonazzoli, Emanuele Perrone, Siming Zhao, Gulden Menderes, Gary Altwerger, Chanhee Han, Burak Zeybek, Anna Bianchi, Aranzazu Manzano, Paola Manara, Emiliano Cocco, Natalia Buza, Pei Hui, Serena Wong, Antonella Ravaggi, El

Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs

转座因子的沉默可能不是灵长类 iPSC 调控进化的主要驱动因素

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.33084

Michelle C Ward, Siming Zhao, Kaixuan Luo, Bryan J Pavlovic, Mohammad M Karimi, Matthew Stephens, Yoav Gilad

信号转导

发表日期：2018

文献求助收藏

Dual CCNE1/PIK3CA targeting is synergistic in CCNE1-amplified/PIK3CA-mutated uterine serous carcinomas in vitro and in vivo

CCNE1/PIK3CA 双靶向作用在体外和体内 CCNE1 扩增/PIK3CA 突变的子宫浆液性癌中具有协同作用

期刊:British Journal of Cancer

影响因子:6.4

doi:10.1038/bjc.2016.198

Emiliano Cocco, Salvatore Lopez, Jonathan Black, Stefania Bellone, Elena Bonazzoli, Federica Predolini, Francesca Ferrari, Carlton L Schwab, Gulden Menderes, Luca Zammataro, Natalia Buza, Pei Hui, Serena Wong, Siming Zhao, Yalai Bai, David L Rimm, Elena Ratner, Babak Litkouhi, Dan-Arin Silasi, Masou

肿瘤

发表日期：2016

文献求助收藏

Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial-mesenchymal transition

子宫和卵巢癌肉瘤的突变图谱表明组蛋白基因参与了上皮-间质转化

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:

doi:10.1073/pnas.1614120113

Siming Zhao, Stefania Bellone, Salvatore Lopez, Durga Thakral, Carlton Schwab, Diana P English, Jonathan Black, Emiliano Cocco, Jungmin Choi, Luca Zammataro, Federica Predolini, Elena Bonazzoli, Mark Bi, Natalia Buza, Pei Hui, Serena Wong, Maysa Abu-Khalaf, Antonella Ravaggi, Eliana Bignotti, Elisab

Clinical validation and literature review of robot-assisted cerebral angiography

机器人辅助脑血管造影术的临床验证和文献综述

Efficacy and Safety of Biosimilar QL1207 vs. the Reference Aflibercept for Patients with Neovascular Age-Related Macular Degeneration: A Randomized Phase 3 Trial

生物类似药QL1207与参考药物阿柏西普治疗新生血管性年龄相关性黄斑变性的疗效和安全性：一项随机3期试验

Baicalein-A Potent Pro-Homeostatic Regulator of Microglia in Retinal Ischemic Injury

黄芩苷——视网膜缺血损伤中小胶质细胞的强效促稳态调节剂

Oral Administration of Branched-Chain Amino Acids Attenuates Atherosclerosis by Inhibiting the Inflammatory Response and Regulating the Gut Microbiota in ApoE-Deficient Mice

口服支链氨基酸可通过抑制炎症反应和调节肠道菌群来减轻ApoE缺陷小鼠的动脉粥样硬化

Novel Insights Into the Sulfated Glucuronic Acid-Based Anti-SARS-CoV-2 Mechanism of Exopolysaccharides From Halophilic Archaeon Haloarcula hispanica

嗜盐古菌西班牙盐弧菌胞外多糖中硫酸葡萄糖醛酸抗SARS-CoV-2机制的新见解

Detailed modeling of positive selection improves detection of cancer driver genes

正向选择的详细建模可提高癌症驱动基因的检测率

Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy

宫颈癌全外显子组测序确定激活 ERBB2 和 PIK3CA 突变作为联合治疗的靶点

Silencing of transposable elements may not be a major driver of regulatory evolution in primate iPSCs

转座因子的沉默可能不是灵长类 iPSC 调控进化的主要驱动因素

Dual CCNE1/PIK3CA targeting is synergistic in CCNE1-amplified/PIK3CA-mutated uterine serous carcinomas in vitro and in vivo

CCNE1/PIK3CA 双靶向作用在体外和体内 CCNE1 扩增/PIK3CA 突变的子宫浆液性癌中具有协同作用

Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial-mesenchymal transition

子宫和卵巢癌肉瘤的突变图谱表明组蛋白基因参与了上皮-间质转化