日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

TOMM40 suppression promotes neuronal cholesterol imbalance and molecular and behavioral phenotypes of Alzheimer's disease

TOMM40抑制会促进神经元胆固醇失衡以及阿尔茨海默病的分子和行为表型。

期刊:Alzheimers & Dementia
影响因子:11.1
doi:10.1002/alz.71306
Yang, Neil V; Wang, Shaowei; Li, Boyang; Simms, Jeffrey; Dinh, Linsey; Huang, Annie; Oei, Jacob H; Yassine, Hussein N; Krauss, Ronald M
代谢
阿尔茨海默症
神经科学
多发性骨髓瘤
发表日期：2026
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The GluA1 cytoplasmic tail regulates intracellular AMPA receptor trafficking and synaptic transmission onto dentate gyrus GABAergic interneurons, gating response to novelty.

GluA1 胞质尾调节细胞内 AMPA 受体运输和突触传递到齿状回 GABA 能中间神经元，从而控制对新事物的反应。

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-025-03328-y
Leana-Sandoval Gerardo, Madrid Alexis, Kolli Ananth V, Chinn Carlene A, Sandoval Matthew A, Lo Iris, Alizo Vera Vanessa, Simms Jeffrey, Wood Marcelo A, Díaz-Alonso Javier
细胞生物学
神经科学
MAPK/ERK
发表日期：2026
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Cell-type-directed network-correcting combination therapy for Alzheimer's disease.

针对阿尔茨海默病的细胞类型导向网络矫正联合疗法

期刊:Cell
影响因子:42.5
doi:10.1016/j.cell.2025.06.035
Li Yaqiao, Pereda Serras Carlota, Blumenfeld Jessica, Xie Min, Hao Yanxia, Deng Elise, Chun You Young, Holtzman Julia, An Alice, Yoon Seo Yeon, Tang Xinyu, Rao Antara, Woldemariam Sarah, Tang Alice, Zhang Alex, Simms Jeffrey, Lo Iris, Oskotsky Tomiko, Keiser Michael J, Huang Yadong, Sirota Marina
细胞生物学
发表日期：2025
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GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models.

GluN2A NMDA 受体增强可改善 Dravet 综合征和阿尔茨海默病模型中的脑振荡、同步性和认知功能

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2019.12.030
Hanson Jesse E, Ma Keran, Elstrott Justin, Weber Martin, Saillet Sandrine, Khan Abdullah S, Simms Jeffrey, Liu Benjamin, Kim Thomas A, Yu Gui-Qiu, Chen Yelin, Wang Tzu-Ming, Jiang Zhiyu, Liederer Bianca M, Deshmukh Gauri, Solanoy Hilda, Chan Connie, Sellers Benjamin D, Volgraf Matthew, Schwarz Jacob B, Hackos David H, Weimer Robby M, Sheng Morgan, Gill T Michael, Scearce-Levie Kimberly, Palop Jorge J
神经科学
发表日期：2020
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Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats

α3β4*神经元尼古丁乙酰胆碱受体的部分激动剂可降低大鼠的乙醇摄入量和渴求行为

期刊:Neuropsychopharmacology
影响因子:7.1
doi:10.1038/npp.2010.191
Chatterjee, Susmita; Steensland, Pia; Simms, Jeffrey A; Holgate, Joan; Coe, Jotham W; Hurst, Raymond S; Shaffer, Christopher L; Lowe, John; Rollema, Hans; Bartlett, Selena E
信号转导
Rat
神经科学
发表日期：2011
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Induction of multiple reinstatements of ethanol- and sucrose-seeking behavior in Long-Evans rats by the α-2 adrenoreceptor antagonist yohimbine

α-2肾上腺素受体拮抗剂育亨宾可诱导Long-Evans大鼠多次恢复对乙醇和蔗糖的渴求行为

期刊:Psychopharmacology
影响因子:3.3
doi:10.1007/s00213-011-2451-9
Simms, Jeffrey A; Richards, Jemma K; Mill, Douglas; Kanholm, Isabel; Holgate, Joan Y; Bartlett, Selena E
Rat
信号转导
免疫/内分泌
发表日期：2011
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The neurokinin 1 receptor antagonist, ezlopitant, reduces appetitive responding for sucrose and ethanol

神经激肽1受体拮抗剂ezlopitant可降低对蔗糖和乙醇的摄食反应。

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0012527
Steensland, Pia; Simms, Jeffrey A; Nielsen, Carsten K; Holgate, Joan; Bito-Onon, Jade J; Bartlett, Selena E
信号转导
发表日期：2010
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Inhibition of orexin-1/hypocretin-1 receptors inhibits yohimbine-induced reinstatement of ethanol and sucrose seeking in Long-Evans rats

抑制食欲素-1/下丘脑泌素-1受体可抑制Long-Evans大鼠中育亨宾诱导的乙醇和蔗糖渴求的恢复

期刊:Psychopharmacology
影响因子:3.3
doi:10.1007/s00213-008-1136-5
Richards, Jemma K; Simms, Jeffrey A; Steensland, Pia; Taha, Sharif A; Borgland, Stephanie L; Bonci, Antonello; Bartlett, Selena E
Rat
信号转导
免疫/内分泌
神经科学
发表日期：2008
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Intermittent access to 20% ethanol induces high ethanol consumption in Long-Evans and Wistar rats

间歇性接触20%乙醇会导致Long-Evans和Wistar大鼠大量摄入乙醇。

期刊:Alcoholism-Clinical and Experimental Research
影响因子:2.7
doi:10.1111/j.1530-0277.2008.00753.x
Simms, Jeffrey A; Steensland, Pia; Medina, Brian; Abernathy, Kenneth E; Chandler, L Judson; Wise, Roy; Bartlett, Selena E
Rat
发表日期：2008
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