Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture.
槲皮素-3-葡萄糖苷可增加低密度脂蛋白受体 (LDLR) 的表达,减弱前蛋白转化酶枯草杆菌蛋白酶/kexin 9 (PCSK9) 的分泌,并刺激培养的 Huh7 人肝细胞对 LDL 的摄取
期刊:FEBS Open Bio
影响因子:2.3
doi:10.1016/j.fob.2014.08.003
Mbikay Majambu, Sirois Francine, Simoes Sonia, Mayne Janice, Chrétien Michel