日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multiplex design and discovery of proximity handles for programmable proteome editing

用于可编程蛋白质组编辑的多重设计和邻近控制点的发现

Suiter, Chase C; Ahn, Green; Chiu, Melodie; Fu, Yi; Sadre, Shayan; Simon, Jessica J; Lee, David S; Fowler, Douglas M; Maly, Dustin J; Baker, David; Shendure, Jay

Multiplexed profiling of intracellular protein abundance, activity, interactions and druggability with LABEL-seq.

利用 LABEL-seq 对细胞内蛋白质丰度、活性、相互作用和成药性进行多重分析

Simon Jessica J, Fowler Douglas M, Maly Dustin J

Profiling of drug resistance in Src kinase at scale uncovers a regulatory network coupling autoinhibition and catalytic domain dynamics.

大规模分析 Src 激酶的耐药性,揭示了一个将自身抑制和催化结构域动力学耦合起来的调控网络

Chakraborty Sujata, Ahler Ethan, Simon Jessica J, Fang Linglan, Potter Zachary E, Sitko Katherine A, Stephany Jason J, Guttman Miklos, Fowler Douglas M, Maly Dustin J