日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Engineered CAR-T cells targeting the non-functional P2X purinoceptor 7 (P2X7) receptor as a novel treatment for ovarian cancer

针对无功能性 P2X 嘌呤受体 7 (P2X7) 受体的工程化 CAR-T 细胞作为卵巢癌的新治疗方法

Veronika Bandara, Victoria M Niktaras, Vasiliki J Willett, Hayley Chapman, Noor A Lokman, Anne M Macpherson, Silvana Napoli, Batjargal Gundsambuu, Jade Foeng, Timothy J Sadlon, Justin Coombs, Shaun R McColl, Simon C Barry, Martin K Oehler, Carmela Ricciardelli

A disrupted FOXP3 transcriptional signature underpins systemic regulatory T cell insufficiency in early pregnancy failure

FOXP3 转录特征破坏是导致早期妊娠失败的系统性调节性 T 细胞不足的原因

Lachlan M Moldenhauer, Kerrie L Foyle, Jasmine J Wilson, Ying Y Wong, David J Sharkey, Ella S Green, Simon C Barry, M Louise Hull, Sarah A Robertson

Progesterone receptor mediates ovulatory transcription through RUNX transcription factor interactions and chromatin remodelling

孕酮受体通过 RUNX 转录因子相互作用和染色质重塑介导排卵转录

Doan T Dinh, James Breen, Barbara Nicol, Natalie J Foot, David C Bersten, Alaknanda Emery, Kirsten M Smith, Ying Y Wong, Simon C Barry, Humphrey H C Yao, Rebecca L Robker, Darryl L Russell

RELA governs a network of islet-specific metabolic genes necessary for beta cell function

RELA 控制着胰岛特异性代谢基因网络,这些基因是β细胞功能所必需的

Nathan W Zammit, Ying Ying Wong, Stacey N Walters, Joanna Warren, Simon C Barry, Shane T Grey

Identification of the novel FOXP3-dependent Treg cell transcription factor MEOX1 by high-dimensional analysis of human CD4+ T cells

通过对人CD4+ T细胞进行高维分析,鉴定出一种新型的FOXP3依赖性Treg细胞转录因子MEOX1

Kevin Baßler ,Lisa Schmidleithner ,Mehrnoush Hadaddzadeh Shakiba ,Tarek Elmzzahi ,Maren Köhne ,Stefan Floess ,Rebekka Scholz ,Naganari Ohkura ,Timothy Sadlon ,Kathrin Klee ,Anna Neubauer ,Shimon Sakaguchi ,Simon C Barry ,Jochen Huehn ,Lorenzo Bonaguro ,Thomas Ulas ,Marc Beyer

Parallel recovery of chromatin accessibility and gene expression dynamics from frozen human regulatory T cells

从冷冻的人类调节性 T 细胞中并行恢复染色质的可及性和基因表达动态

Ying Y Wong, Jessica E Harbison, Christopher M Hope, Batjargal Gundsambuu, Katherine A Brown, Soon W Wong, Cheryl Y Brown, Jennifer J Couper, Jimmy Breen, Ning Liu, Stephen M Pederson, Maren Köhne, Kathrin Klee, Joachim Schultze, Marc Beyer, Timothy Sadlon, Simon C Barry

SARS-CoV-2 Omicron variant escapes neutralizing antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents

在轻症新冠肺炎康复者中,SARS-CoV-2 Omicron 变异株比其他变异株更能有效地逃避中和抗体和 T 细胞反应。

Pablo Garcia-Valtanen ,Christopher M Hope ,Makutiro G Masavuli ,Arthur Eng Lip Yeow ,Harikrishnan Balachandran ,Zelalem A Mekonnen ,Zahraa Al-Delfi ,Arunasingam Abayasingam ,David Agapiou ,Alberto Ospina Stella ,Anupriya Aggarwal ,George Bouras ,Jason Gummow ,Catherine Ferguson ,Stephanie O'Connor ,Erin M McCartney ,David J Lynn ,Guy Maddern ,Eric J Gowans ,Benjamin A J Reddi ,David Shaw ,Chuan Kok-Lim ,Michael R Beard ,Daniela Weiskopf ,Alessandro Sette ,Stuart G Turville ,Rowena A Bull ,Simon C Barry ,Branka Grubor-Bauk

3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) risk

3DFAACTS-SNP:利用调节性 T 细胞特异性表观基因组学数据揭示 1 型糖尿病 (T1D) 风险的候选机制

Ning Liu #, Timothy Sadlon #, Ying Y Wong, Stephen Pederson, James Breen #, Simon C Barry #

Cord Blood T Cells Expressing High and Low PKCζ Levels Develop into Cells with a Propensity to Display Th1 and Th9 Cytokine Profiles, Respectively

脐带血中表达高水平和低水平PKCζ的T细胞分别发育成为具有Th1和Th9细胞因子谱倾向的细胞。

Khalida Perveen ,Alex Quach ,Andrew McPhee ,Susan L Prescott ,Simon C Barry ,Charles S Hii ,Antonio Ferrante

Optimization of Blood Handling and Peripheral Blood Mononuclear Cell Cryopreservation of Low Cell Number Samples

血液处理优化及低细胞数样本外周血单核细胞冷冻保存

Christopher M Hope, Dao Huynh, Ying Ying Wong, Helena Oakey, Griffith Boord Perkins, Trung Nguyen, Sabrina Binkowski, Minh Bui, Ace Y L Choo, Emily Gibson, Dexing Huang, Ki Wook Kim, Katrina Ngui, William D Rawlinson, Timothy Sadlon, Jennifer J Couper, Megan A S Penno, Simon C Barry, On Behalf Of Th