日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Creation of de novo cryptic splicing for ALS and FTD precision medicine

利用从头隐蔽剪接技术进行ALS和FTD精准医疗

Oscar G Wilkins ,Max Z Y J Chien # ,Josette J Wlaschin # ,Simone Barattucci ,Peter Harley ,Francesca Mattedi ,Puja R Mehta ,Maria Pisliakova ,Eugeni Ryadnov ,Matthew J Keuss ,David Thompson ,Holly Digby ,Lea Knez ,Rebecca L Simkin ,Juan Antinao Diaz ,Matteo Zanovello ,Anna-Leigh Brown ,Annalucia Darbey ,Rajvinder Karda ,Elizabeth M C Fisher ,Thomas J Cunningham ,Claire E Le Pichon ,Jernej Ule ,Pietro Fratta

Loss of TDP-43 induces synaptic dysfunction that is rescued by UNC13A splice-switching ASOs

TDP-43 缺失会诱发突触功能障碍,而 UNC13A 剪接转换 ASO 可以挽救这一现象

Matthew J Keuss, Peter Harley, Eugeni Ryadnov, Rachel E Jackson, Matteo Zanovello, Oscar G Wilkins, Simone Barattucci, Puja R Mehta, Marcio G Oliveira, Joanna E Parkes, Aparna Sinha, Andrés F Correa-Sánchez, Peter L Oliver, Elizabeth M C Fisher, Giampietro Schiavo, Mala Shah, Juan Burrone, Pietro Fr

TDP-43 loss induces extensive cryptic polyadenylation in ALS/FTD

TDP-43 缺失在 ALS/FTD 中诱导大量隐秘性多聚腺苷酸化

Sam Bryce-Smith, Anna-Leigh Brown, Puja R Mehta, Francesca Mattedi, Alla Mikheenko, Simone Barattucci, Matteo Zanovello, Dario Dattilo, Matthew Yome, Sarah E Hill, Yue A Qi, Oscar G Wilkins, Kai Sun, Eugeni Ryadnov, Yixuan Wan; NYGC ALS Consortium; Jose Norberto S Vargas, Nicol Birsa, Towfique Raj, 

Neuropathology of the Basal Ganglia in SNCA Transgenic Rat Model of Parkinson's Disease: Involvement of Parvalbuminergic Interneurons and Glial-Derived Neurotropic Factor

帕金森病 SNCA 转基因大鼠模型的基底神经节神经病理学:小白蛋白中间神经元和胶质衍生神经营养因子的参与

Emanuela Paldino, Vincenza D'angelo, Mariangela Massaro Cenere, Ezia Guatteo, Simone Barattucci, Giorgia Migliorato, Nicola Berretta, Olaf Riess, Giuseppe Sancesario, Nicola Biagio Mercuri, Francesca Romana Fusco