日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency

Nivolumab 对高突变负荷和错配修复缺陷儿童癌症的疗效

Anirban Das, Uri Tabori, Lauren C Sambira Nahum, Natalie B Collins, Rebecca Deyell, Rina Dvir, Cecile Faure-Conter, Timothy E Hassall, Jane E Minturn, Melissa Edwards, Elissa Brookes, Vanessa Bianchi, Adrian Levine, Simone C Stone, Sumedha Sudhaman, Santiago Sanchez Ramirez, Ayse B Ercan, Lucie Sten

Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency

种系 DNA 复制修复缺陷儿童对 PD-1 抑制反应的基因组预测因子

Anirban Das #, Sumedha Sudhaman #, Daniel Morgenstern #, Ailish Coblentz, Jiil Chung, Simone C Stone, Noor Alsafwani, Zhihui Amy Liu, Ola Abu Al Karsaneh, Shirin Soleimani, Hagay Ladany, David Chen, Matthew Zatzman, Vanja Cabric, Liana Nobre, Vanessa Bianchi, Melissa Edwards, Lauren C Sambira Nahum,

Mutations in the RAS/MAPK Pathway Drive Replication Repair-Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition

RAS/MAPK 通路突变会引发复制修复缺陷型高突变肿瘤,并使其对 MEK 抑制产生敏感性

Brittany B Campbell #, Melissa A Galati #, Simone C Stone, Alexandra N Riemenschneider, Melissa Edwards, Sumedha Sudhaman, Robert Siddaway, Martin Komosa, Nuno M Nunes, Liana Nobre, A Sorana Morrissy, Matthew Zatzman, Michal Zapotocky, Lazar Joksimovic, Sangeetha N Kalimuthu, David Samuel, Gary Maso

Local and Systemic STAT3 and p65 NF-KappaB Expression as Progression Markers and Functional Targets for Patients With Cervical Cancer

局部和系统性 STAT3 和 p65 NF-κB 表达作为宫颈癌患者的进展标志和功能靶点

Renata A M Rossetti, Ildefonso A da Silva-Junior, Gretel R Rodríguez, Karla L F Alvarez, Simone C Stone, Marcella Cipelli, Caio R F Silveira, Mariana Carmezim Beldi, Giana R Mota, Paulo F R Margarido, Edmund C Baracat, Miyuki Uno, Luisa L Villa, Jesus P Carvalho, Kaori Yokochi, Maria Beatriz S F Ros

Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma

卵巢癌中的调节性 T 细胞具有与黑色素瘤不同的高度活跃的表型

Aras Toker, Linh T Nguyen, Simone C Stone, S Y Cindy Yang, Sarah Rachel Katz, Patricia A Shaw, Blaise A Clarke, Danny Ghazarian, Ayman Al-Habeeb, Alexandra Easson, Wey L Leong, David R McCready, Michael Reedijk, Cynthia J Guidos, Trevor J Pugh, Marcus Q Bernardini, Pamela S Ohashi