日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Hypofractionated radiotherapy combined with lenalidomide improves systemic antitumor activity in mouse solid tumor models

低分割放射疗法联合来那度胺可提高小鼠实体瘤模型的全身抗肿瘤活性。

Kateryna Onyshchenko ,Ren Luo ,Xi Rao ,Xuanwei Zhang ,Simone Gaedicke ,Anca-Ligia Grosu ,Elke Firat ,Gabriele Niedermann

Expansion of circulating stem-like CD8+ T cells by adding CD122-directed IL-2 complexes to radiation and anti-PD1 therapies in mice

在小鼠中,通过在放射疗法和抗PD-1疗法中添加CD122靶向的IL-2复合物,可以扩增循环干细胞样CD8+ T细胞。

Kateryna Onyshchenko ,Ren Luo ,Elena Guffart ,Simone Gaedicke ,Anca-Ligia Grosu ,Elke Firat ,Gabriele Niedermann

Adding liposomal doxorubicin enhances the abscopal effect induced by radiation/αPD1 therapy depending on tumor cell mitochondrial DNA and cGAS/STING

添加脂质体阿霉素可增强放射/αPD1 疗法诱导的远隔效应,这取决于肿瘤细胞线粒体 DNA 和 cGAS/STING

Liqun Wang #, Ren Luo #, Kateryna Onyshchenko, Xi Rao, Meidan Wang, Beatrice Menz, Simone Gaedicke, Anca-Ligia Grosu, Elke Firat, Gabriele Niedermann

Necroptosis-dependent Immunogenicity of Cisplatin: Implications for Enhancing the Radiation-induced Abscopal Effect

顺铂的坏死凋亡依赖性免疫原性:对增强放射诱导的远隔效应的影响

Ren Luo, Kateryna Onyshchenko, Liqun Wang, Simone Gaedicke, Anca-Ligia Grosu, Elke Firat, Gabriele Niedermann

Immune cell infiltration pattern in non-small cell lung cancer PDX models is a model immanent feature and correlates with a distinct molecular and phenotypic make-up

非小细胞肺癌 PDX 模型中的免疫细胞浸润模式是模型的内在特征,与独特的分子和表型组成相关

Eva Oswald, Daniel Bug, Anne Grote, Kanstantsin Lashuk, Nassim Bouteldja, Dorothee Lenhard, Anne Löhr, Anke Behnke, Volker Knauff, Anna Edinger, Kerstin Klingner, Simone Gaedicke, Gabriele Niedermann, Dorit Merhof, Friedrich Feuerhake, Julia Schueler

Cisplatin Facilitates Radiation-Induced Abscopal Effects in Conjunction with PD-1 Checkpoint Blockade Through CXCR3/CXCL10-Mediated T-cell Recruitment

顺铂通过 CXCR3/CXCL10 介导的 T 细胞募集促进放射诱导的远隔效应与 PD-1 检查点阻断相结合

Ren Luo, Elke Firat, Simone Gaedicke, Elena Guffart, Tsubasa Watanabe, Gabriele Niedermann

Noninvasive positron emission tomography and fluorescence imaging of CD133+ tumor stem cells

CD133+ 肿瘤干细胞的无创正电子发射断层扫描和荧光成像

Simone Gaedicke, Friederike Braun, Shruthi Prasad, Marcia Machein, Elke Firat, Michael Hettich, Ravindra Gudihal, Xuekai Zhu, Kerstin Klingner, Julia Schüler, Christel C Herold-Mende, Anca-Ligia Grosu, Martin Behe, Wolfgang Weber, Helmut Mäcke, Gabriele Niedermann

Chloroquine or chloroquine-PI3K/Akt pathway inhibitor combinations strongly promote γ-irradiation-induced cell death in primary stem-like glioma cells

氯喹或氯喹-PI3K/Akt 通路抑制剂组合强烈促进原发性干细胞样胶质瘤细胞中 γ 射线诱导的细胞死亡

Elke Firat, Astrid Weyerbrock, Simone Gaedicke, Anca-Ligia Grosu, Gabriele Niedermann