Co-targeting SOS1 enhances the antitumor effects of KRASG12C inhibitors by addressing intrinsic and acquired resistance
共靶向 SOS1 可通过解决内在和获得性耐药性增强 KRASG12C 抑制剂的抗肿瘤作用
期刊:Nature Cancer
影响因子:23.5
doi:10.1038/s43018-024-00800-6
Venu Thatikonda #, Hengyu Lyu #, Sabine Jurado, Kaja Kostyrko, Christopher A Bristow, Christoph Albrecht, Donat Alpar, Heribert Arnhof, Oliver Bergner, Karin Bosch, Ningping Feng, Sisi Gao, Daniel Gerlach, Michael Gmachl, Melanie Hinkel, Simone Lieb, Astrid Jeschko, Annette A Machado, Thomas Madensk