日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting phospholipase PLAG-15 promotes healthy aging in C. elegans via lysosomal-related genes.

靶向磷脂酶 PLAG-15 通过溶酶体相关基因促进秀丽隐杆线虫的健康衰老

van der Rijt Sanne, Molenaars Marte, Kamble Rashmi, Li Weisha, Schomakers Bauke V, Dane Adrie D, Denis Simone W, van Weeghel Michel, Vaz Frédéric M, Tammaro Alessandra, Janssens Georges E, Gao Arwen W, Houtkooper Riekelt H

Author Correction: Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells

作者更正:AMPK-FOXO1-PDK4通路的激活是tafazzin缺陷细胞中丙酮酸脱氢酶活性降低的主要机制。

Liang, Zhuqing; Ralph-Epps, Tyler; Schmidtke, Michael W; Lazcano, Pablo; Denis, Simone W; Balážová, Mária; Teixeira da Rosa, Nevton Jr; Chakkour, Mohamed; Hazime, Sanaa; Ren, Mindong; Schlame, Michael; Houtkooper, Riekelt H; Greenberg, Miriam L

Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells

AMPK-FOXO1-PDK4 通路的上调是 tafazzin 缺乏细胞中丙酮酸脱氢酶活性降低的主要机制

Zhuqing Liang, Tyler Ralph-Epps, Michael W Schmidtke, Pablo Lazcano, Simone W Denis, Mária Balážová, Nevton Teixeira da Rosa Jr, Mohamed Chakkour, Sanaa Hazime, Mindong Ren, Michael Schlame, Riekelt H Houtkooper, Miriam L Greenberg

Human inborn errors of long-chain fatty acid oxidation show impaired inflammatory responses to TLR4-ligand LPS

人类先天性长链脂肪酸氧化缺陷会导致对 TLR4 配体 LPS 的炎症反应受损。

Signe Mosegaard ,Krishna S Twayana ,Simone W Denis ,Jeffrey Kroon ,Bauke V Schomakers ,Michel van Weeghel ,Riekelt H Houtkooper ,Rikke K J Olsen ,Christian K Holm

Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells

AMPK-FOXO1-PDK4 通路的上调是丙酮酸脱氢酶活性降低的主要机制,并导致缺乏 tafazzin 的细胞对葡萄糖的吸收增加

Zhuqing Liang, Tyler Ralph-Epps, Michael W Schmidtke, Pablo Lazcano, Simone W Denis, Mária Balážová, Mohamed Chakkour, Sanaa Hazime, Mindong Ren, Michael Schlame, Riekelt H Houtkooper, Miriam L Greenberg

Association between Genetic Variants and Peripheral Neuropathy in Patients with NSCLC Treated with First-Line Platinum-Based Therapy

一线铂类化疗治疗的非小细胞肺癌患者中,基因变异与周围神经病变之间的关联

de Jong, Corine; Herder, Gerarda J M; van Haarlem, Simone W A; van der Meer, Femke S; van Lindert, Anne S R; Ten Heuvel, Alexandra; Brouwer, Jan; Egberts, Toine C G; Deneer, Vera H M

The association between skeletal muscle measures and chemotherapy-induced toxicity in non-small cell lung cancer patients

非小细胞肺癌患者骨骼肌指标与化疗引起的毒性之间的关联

de Jong, Corine; Chargi, Najiba; Herder, Gerarda J M; van Haarlem, Simone W A; van der Meer, Femke; van Lindert, Anne S R; Ten Heuvel, Alexandra; Brouwer, Jan; de Jong, Pim A; Devriese, Lot A; Huitema, Alwin D R; Egberts, Toine C G; de Bree, Remco; Deneer, Vera H M

Lower Metabolic Potential and Impaired Metabolic Flexibility in Human Lymph Node Stromal Cells from Patients with Rheumatoid Arthritis

类风湿关节炎患者淋巴结基质细胞代谢潜力较低、代谢灵活性受损

Tineke A de Jong, Johanna F Semmelink, Simone W Denis, Janne W Bolt, Mario Maas, Marleen G H van de Sande, Riekelt H L Houtkooper, Lisa G M van Baarsen

Racial Disparities in Incidence of Legionnaires' Disease and Social Determinants of Health: A Narrative Review

军团病发病率的种族差异与健康社会决定因素:一项叙述性综述

Hunter, Candis M; Salandy, Simone W; Smith, Jessica C; Edens, Chris; Hubbard, Brian

Association between Genetic Variants and Cisplatin-Induced Nephrotoxicity: A Genome-Wide Approach and Validation Study

遗传变异与顺铂诱导肾毒性的关联:全基因组方法及验证研究

Zazuli, Zulfan; de Jong, Corine; Xu, Wei; Vijverberg, Susanne J H; Masereeuw, Rosalinde; Patel, Devalben; Mirshams, Maryam; Khan, Khaleeq; Cheng, Dangxiao; Ordonez-Perez, Bayardo; Huang, Shaohui; Spreafico, Anna; Hansen, Aaron R; Goldstein, David P; de Almeida, John R; Bratman, Scott V; Hope, Andrew; Knox, Jennifer J; Wong, Rebecca K S; Darling, Gail E; Kitchlu, Abhijat; van Haarlem, Simone W A; van der Meer, Femke; van Lindert, Anne S R; Ten Heuvel, Alexandra; Brouwer, Jan; Ross, Colin J D; Carleton, Bruce C; Egberts, Toine C G; Herder, Gerarda J M; Deneer, Vera H M; Maitland-van der Zee, Anke H; Liu, Geoffrey