日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Distinct neuronal alterations distinguish two subtypes of sporadic Creutzfeldt-Jakob disease with shared dysfunctional pathways.

散发性克雅氏病的两个亚型具有不同的神经元改变,但它们都存在共同的功能障碍通路。

Williams Katie, Groveman Bradley R, Foliaki Simote T, Race Brent, Hay Arielle, Walters Ryan O, Thomas Tina, Zanusso Gianluigi, Carroll James A, Haigh Cathryn L

Prion-induced ferroptosis is facilitated by RAC3.

RAC3 促进朊病毒诱导的铁死亡

Peng Hao, Pfeiffer Susanne, Varynskyi Borys, Qiu Marina, Srinark Chanikarn, Jin Xiang, Zhang Xin, Williams Katie, Groveman Bradley R, Foliaki Simote T, Race Brent, Thomas Tina, Chen Chengxuan, Müller Constanze, Kovács Krisztina, Arzberger Thomas, Momma Stefan, Haigh Cathryn L, Schick Joel A

Proteasome mutations associated with CANDLE syndrome cause altered neuronal development by dysregulating polyamine synthesis.

与 CANDLE 综合征相关的蛋白酶体突变通过扰乱多胺合成导致神经元发育异常

Winkler Clayton W, Schwarz Benjamin, Williams Katie, Alehashemi Sara, Foliaki Simote T, Snow Joseph, Joseph Lisa, Thurm Audrey, Friend Christopher, Cooper Gwendolyn, Bohrnsen Eric, Bhuyan Farzana, Brandes Nathan T, Moaddel Ruin, Boehm Manfred, Chen Guibin, Kimzey Cole D, Bielekova Bibiana, Kocot Joanna, Kosa Peter, Haigh Cathryn L, Goldbach-Mansky Raphaela, Peterson Karin E

Lack of Transmission of Chronic Wasting Disease Prions to Human Cerebral Organoids

慢性消耗性疾病朊病毒无法传播至人类脑类器官

Bradley R Groveman, Katie Williams, Brent Race, Simote Foliaki, Tina Thomas, Andrew G Hughson, Ryan O Walters, Wenquan Zou, Cathryn L Haigh

Limbic system synaptic dysfunctions associated with prion disease onset

与朊病毒疾病发病相关的边缘系统突触功能障碍

Simote T Foliaki, Bradley R Groveman, Emmett A Dews, Katie Williams, Hadil El Soufi, Benjamin Schwarz, Jacqueline M Leung, Christine A Schneider, Cindi L Schwartz, Eric Bohrnsen, Cole D Kimzey, Brent Race, Cathryn L Haigh

Temporary alteration of neuronal network communication is a protective response to redox imbalance that requires GPI-anchored prion protein

神经网络通讯的暂时改变是对氧化还原失衡的保护性反应,需要 GPI 锚定的朊病毒蛋白

Simote T Foliaki, Aleksandar Wood, Katie Williams, Anna Smith, Ryan O Walters, Chase Baune, Bradley R Groveman, Cathryn L Haigh

Neural cell engraftment therapy for sporadic Creutzfeldt-Jakob disease restores neuroelectrophysiological parameters in a cerebral organoid model

散发性克雅氏病的神经细胞移植治疗可恢复脑类器官模型中的神经电生理参数

Katie Williams, Simote T Foliaki, Brent Race, Anna Smith, Tina Thomas, Bradley R Groveman, Cathryn L Haigh

Sporadic Creutzfeldt-Jakob disease infected human cerebral organoids retain the original human brain subtype features following transmission to humanized transgenic mice

散发型克雅氏病感染的人类脑类器官在传播至人源化转基因小鼠后,仍保留了原始人类脑亚型的特征。

Groveman, Bradley R; Race, Brent; Foliaki, Simote T; Williams, Katie; Hughson, Andrew G; Baune, Chase; Zanusso, Gianluigi; Haigh, Cathryn L

Prion propagation and cellular dysfunction in prion disease: Disconnecting the dots

朊病毒疾病中朊病毒的增殖和细胞功能障碍:理清头绪

Foliaki, Simote T; Haigh, Cathryn L

A PrP EGFR signaling axis controls neural stem cell senescence through modulating cellular energy pathways

PrP EGFR信号轴通过调节细胞能量通路控制神经干细胞衰老

Bradley R Groveman ,Benjamin Schwarz ,Eric Bohrnsen ,Simote T Foliaki ,James A Carroll ,Aleksandar R Wood ,Catharine M Bosio ,Cathryn L Haigh