日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Next generation protein-corrole bio-assemblies provide effective tumoricidal treatment in a metastatic triple-negative breast cancer model

新一代蛋白质-咕啉生物组装体在转移性三阴性乳腺癌模型中提供有效的肿瘤杀伤治疗

Sharma, Vinay K; Gonzalez-Almeyda, Nelyda; Mikhael, Simoun; Cho, Ryan H; Aceves, Joseph; Ishaya, Kristin; Kim, Sun Woo; Wiesenthal, Abby; Benhaghnazar, Rebecca; Babajani, Amirhesam; Abrol, Ravinder; Gray, Harry B; Gross, Zeev; Medina Kauwe, Lali

Systemic HER3 ligand-mimicking nanobioparticles enter the brain and reduce intracranial tumour growth.

模拟 HER3 配体的全身性纳米生物颗粒进入大脑,减少颅内肿瘤的生长

Alonso-Valenteen Felix, Mikhael Simoun, Wang HongQiang, Sims Jessica, Taguiam Michael, Teh James, Sances Sam, Wong Michelle, Miao Tianxin, Srinivas Dustin, Gonzalez-Almeyda Nelyda, Cho Ryan H, Sanchez Romny, Nguyenle Kimngan, Serrano Erik, Ondatje Briana, Benhaghnazar Rebecca L, Gray Harry B, Gross Zeev, Yu John, Svendsen Clive N, Abrol Ravinder, Medina-Kauwe Lali K

Barriers and drivers to consuming neglected and underutilized species: evidence from six European countries

阻碍和影响人们消费被忽视和未充分利用物种的因素:来自六个欧洲国家的证据

Bayudan, Simoun; Zagata, Lukas; Plzakova, Lucie; De Steur, Hans; Schouteten, Joachim Jietse

Mind the Gaps: The Need for Inclusion of Male-Identified Voices in Adolescent Sexual and Reproductive Health

关注差距:青少年性与生殖健康领域需要纳入男性声音

Valdez, Elizabeth Salerno; Valdez, Luis; Gorry, Eddie; Chan, Jazmine; Dixon, Saharra; Fisher, Tiarra; Simoun, Alya; Weil, Mira; Collins-Lovell, Camille; Egan, Justine; Gubrium, Aline

Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis

肠道胆汁酸为艰难梭菌 TcdB 诱发的疾病发病机制提供了一道可克服的屏障

Simoun Icho, Jennifer S Ward, John Tam, Larry K Kociolek, Casey M Theriot, Roman A Melnyk

Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo

新型强效氮杂环丁烷类化合物可不可逆地抑制Stat3活化,并在体内诱导抗肿瘤反应,抑制人乳腺肿瘤生长。

Yue, Peibin; Zhu, Yinsong; Brotherton-Pleiss, Christine; Fu, Wenzhen; Verma, Nagendra; Chen, Jasmine; Nakamura, Kayo; Chen, Weiliang; Chen, Yue; Alonso-Valenteen, Felix; Mikhael, Simoun; Medina-Kauwe, Lali; Kershaw, Kathleen M; Celeridad, Maria; Pan, Songqin; Limpert, Allison S; Sheffler, Douglas J; Cosford, Nicholas D P; Shiao, Stephen L; Tius, Marcus A; Lopez-Tapia, Francisco; Turkson, James

Dual Inhibition of Vacuolar-ATPase and TMPRSS2 Is Required for Complete Blockade of SARS-CoV-2 Entry into Cells

双重抑制液泡ATPase和TMPRSS2是完全阻断SARS-CoV-2进入细胞所必需的

Simoun Icho ,Edurne Rujas ,Krithika Muthuraman ,John Tam ,Huazhu Liang ,Shelby Landreth ,Mingmin Liao ,Darryl Falzarano ,Jean-Philippe Julien ,Roman A Melnyk

Discovery of Novel Azetidine Amides as Potent Small-Molecule STAT3 Inhibitors

发现新型氮杂环丁烷酰胺类化合物作为强效小分子STAT3抑制剂

Brotherton-Pleiss, Christine; Yue, Peibin; Zhu, Yinsong; Nakamura, Kayo; Chen, Weiliang; Fu, Wenzhen; Kubota, Casie; Chen, Jasmine; Alonso-Valenteen, Felix; Mikhael, Simoun; Medina-Kauwe, Lali; Tius, Marcus A; Lopez-Tapia, Francisco; Turkson, James

Intestinal bile acids directly modulate the structure and function of C. difficile TcdB toxin

肠道胆汁酸直接调节艰难梭菌 TcdB 毒素的结构和功能

John Tam, Simoun Icho, Evelyn Utama, Kathleen E Orrell, Rodolfo F Gómez-Biagi, Casey M Theriot, Heather K Kroh, Stacey A Rutherford, D Borden Lacy, Roman A Melnyk

HER3-targeted protein chimera forms endosomolytic capsomeres and self-assembles into stealth nucleocapsids for systemic tumor homing of RNA interference in vivo

HER3 靶向蛋白嵌合体形成胞内溶酶体壳粒并自组装成隐形核衣壳,用于体内 RNA 干扰的系统性肿瘤归巢

Felix Alonso-Valenteen, Sayuri Pacheco, Dustin Srinivas, Altan Rentsendorj, David Chu, Jay Lubow, Jessica Sims, Tianxin Miao, Simoun Mikhael, Jae Youn Hwang, Ravinder Abrol, Lali K Medina Kauwe