日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lipophilic but not hydrophilic statin therapy improves cardiodynamics without affecting skeletal muscle morphology or function in geriatric Wistar rats

亲脂性而非亲水性他汀类药物治疗可改善老年Wistar大鼠的心脏动力学,且不影响骨骼肌的形态或功能。

Rebalka, Irena A; Alshamali, Razan; vanLieshout, Tiffany L; Gingrich, Molly A; Marlatt, Matthew R; Ljubicic, Vladimir; Simpson, Jeremy A; Hawke, Thomas J

Mitochondrial-targeted plastoquinone therapy prevents early onset muscle weakness that occurs before atrophy during ovarian cancer.

线粒体靶向质体醌疗法可预防卵巢癌萎缩前发生的早期肌肉无力

Delfinis Luca J, Khajehzadehshoushtar Shahrzad, Flewwelling Luke D, Andrews Nathaniel J, Garibotti Madison C, Gandhi Shivam, Brahmbhatt Aditya N, Morris Brooke A, Garlisi Bianca, Lauks Sylvia, Aitken Caroline, Ogilvie Leslie, Tsitkanou Stavroula, Simpson Jeremy A, Greene Nicholas P, Cheng Arthur J, Petrik Jim, Perry Christopher G R

Adiponectin-receptor agonism prevents right ventricular tissue pathology in a mouse model of Duchenne muscular dystrophy.

脂联素受体激动剂可预防杜氏肌营养不良症小鼠模型的右心室组织病变

Gandhi Shivam, Delfinis Luca J, Bhatt Parashar D, Garibotti Madison C, Bellissimo Catherine A, Goli Amireza N, Morris Brooke A, Brahmbhatt Aditya N, Yakobov-Shimonov Simona, Rahman Fasih A, Quadrilatero Joe, Simpson Jeremy A, Sweeney Gary, Abdul-Sater Ali A, Backx Peter H, Hsu Henry H, Perry Christopher G R

Mitohormesis during advanced stages of Duchenne muscular dystrophy reveals a redox-sensitive creatine pathway that can be enhanced by the mitochondrial-targeting peptide SBT-20

杜氏肌营养不良症晚期线粒体兴奋效应揭示了一种氧化还原敏感的肌酸通路,该通路可被线粒体靶向肽SBT-20增强。

Hughes, Meghan C; Ramos, Sofhia V; Brahmbhatt, Aditya N; Turnbull, Patrick C; Polidovitch, Nazari N; Garibotti, Madison C; Schlattner, Uwe; Hawke, Thomas J; Simpson, Jeremy A; Backx, Peter H; Perry, Christopher Gr

Yap Is a Nutrient Sensor Sensitive to the Amino Acid L-Isoleucine and Regulates the Expression of Ctgf in Cardiomyocytes

Yap是一种对氨基酸L-异亮氨酸敏感的营养传感器,能够调节心肌细胞中Ctgf的表达。

Nelson, Victoria L; Eadie, Ashley L; Perez, Lester; Madhu, Malav; Platt, Mathew; Mercer, Angella; Pulinilkunnil, Thomas; Kienesberger, Petra; Simpson, Jeremy A; Brunt, Keith R

Cardiac fibroblasts: answering the call

心脏成纤维细胞:响应召唤

Kleinbongard, Petra; Senyo, Samuel E; Lindsey, Merry L; Garvin, Alexandra M; Simpson, Jeremy A; de Castro Braz, Lisandra E

Teaching an old drug new tricks: Regulatory insights for the repurposing of hemin in cardiovascular disease

赋予老药新用途:血红素在心血管疾病治疗中的监管启示

Eadie, Ashley L; Simpson, Jeremy A; Brunt, Keith R

Better Respiratory Function in Heart Failure Patients With Use of Central-Acting Therapeutics

使用中枢作用药物可改善心力衰竭患者的呼吸功能

Vishram-Nielsen, Julie K K; Scolari, Fernando Luis; Steve Fan, Chun-Po; Moayedi, Yas; Ross, Heather J; Manlhiot, Cedric; Allwood, Melissa A; Alba, Ana Carolina; Brunt, Keith R; Simpson, Jeremy A; Billia, Filio

An Evaluation of Cardiac Health in the Spontaneously Hypertensive Rat Colony: Implications of Evolutionary Driven Increases in Concentric Hypertrophy

自发性高血压大鼠群心脏健康状况评估:向心性肥厚进化驱动增加的意义

Holjak, Emma J B; Savinova, Iryna; Nelson, Victoria L; Ogilvie, Leslie M; Ng, Anabelle M; Edgett, Brittany A; Platt, Mathew J; Brunt, Keith R; Ask, Kjetil; Simpson, Jeremy A

A new approach to improve the hemodynamic assessment of cardiac function independent of respiratory influence

一种无需呼吸影响即可改善心脏功能血流动力学评估的新方法

Ogilvie, Leslie M; Edgett, Brittany A; Gray, Simon; Al-Mufty, Sally; Huber, Jason S; Brunt, Keith R; Simpson, Jeremy A