Simpson Melanie A相关文献与解析，生知库

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer

葡萄糖醛酸化作用的改变会扰乱雄激素依赖性反应模式，并标志着前列腺癌的去势抵抗。

Zimmer, Brenna M; Howell, Michelle E; Ma, Linlin; Enders, Jeffrey R; Lehman, Danielle; Corey, Eva; Barycki, Joseph J; Simpson, Melanie A

肿瘤

Prostate tumor cell exosomes containing hyaluronidase Hyal1 stimulate prostate stromal cell motility by engagement of FAK-mediated integrin signaling

含有透明质酸酶Hyal1的前列腺肿瘤细胞外泌体通过激活FAK介导的整合素信号通路刺激前列腺基质细胞的运动。

期刊:Matrix Biology

影响因子:4.8

doi:10.1016/j.matbio.2018.05.002

McAtee, Caitlin O; Booth, Christine; Elowsky, Christian; Zhao, Lei; Payne, Jeremy; Fangman, Teresa; Caplan, Steve; Henry, Michael D; Simpson, Melanie A

Molecular Pharmacodynamics-Guided Scheduling of Biologically Effective Doses: A Drug Development Paradigm Applied to MET Tyrosine Kinase Inhibitors

基于分子药效学的生物有效剂量给药方案：一种应用于MET酪氨酸激酶抑制剂的药物开发范式

期刊:Molecular Cancer Therapeutics

影响因子:5.5

doi:10.1158/1535-7163.MCT-17-0552

Srivastava, Apurva K; Hollingshead, Melinda G; Govindharajulu, Jeevan Prasaad; Covey, Joseph M; Liston, Dane; Simpson, Melanie A; Peggins, James O; Bottaro, Donald P; Wright, John J; Kinders, Robert J; Doroshow, James H; Parchment, Ralph E

Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential

前列腺肿瘤细胞对外部雄激素依赖性的丧失与葡萄糖醛酸化潜能的升高有关。

期刊:Hormones & Cancer

影响因子:

doi:10.1007/s12672-016-0268-z

Zimmer, Brenna M; Howell, Michelle E; Wei, Qin; Ma, Linlin; Romsdahl, Trevor; Loughman, Eileen G; Markham, Jennifer E; Seravalli, Javier; Barycki, Joseph J; Simpson, Melanie A

Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis

Dnmt3b 的甲基化非依赖性抑制促进了 Dnmt3a 在小鼠 MYC 诱导的 T 细胞淋巴瘤发生中的致癌活性

期刊:Oncogene

影响因子:7.3

doi:10.1038/onc.2014.472

Haney, Staci L; Hlady, Ryan A; Opavska, Jana; Klinkebiel, David; Pirruccello, Samuel J; Dutta, Samikshan; Datta, Kaustubh; Simpson, Melanie A; Wu, Lizhao; Opavsky, Rene

DNA甲基化

发表日期：2015

文献求助收藏

Advances in Hyaluronan Biology: Signaling, Regulation, and Disease Mechanisms

透明质酸生物学进展：信号传导、调控和疾病机制

期刊:International Journal of Cell Biology

影响因子:

doi:10.1155/2015/690572

Simpson, Melanie A; de la Motte, Carol; Sherman, Larry S; Weigel, Paul H

信号转导

发表日期：2015

文献求助收藏

Impacts of Hyaluronan on Extracellular Vesicle Production and Signaling

透明质酸对细胞外囊泡生成和信号传导的影响

Recent insights into the implications of UGDH mutations for human developmental disease

近期对UGDH突变对人类发育疾病影响的认识

Mechanisms of coordinating hyaluronan and glycosaminoglycan production by nucleotide sugars

核苷酸糖协调透明质酸和糖胺聚糖生成的机制

Integration of Sugar Metabolism and Proteoglycan Synthesis by UDP-glucose Dehydrogenase

UDP-葡萄糖脱氢酶整合糖代谢和蛋白聚糖合成

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer

葡萄糖醛酸化作用的改变会扰乱雄激素依赖性反应模式，并标志着前列腺癌的去势抵抗。

Prostate tumor cell exosomes containing hyaluronidase Hyal1 stimulate prostate stromal cell motility by engagement of FAK-mediated integrin signaling

含有透明质酸酶Hyal1的前列腺肿瘤细胞外泌体通过激活FAK介导的整合素信号通路刺激前列腺基质细胞的运动。

Molecular Pharmacodynamics-Guided Scheduling of Biologically Effective Doses: A Drug Development Paradigm Applied to MET Tyrosine Kinase Inhibitors

基于分子药效学的生物有效剂量给药方案：一种应用于MET酪氨酸激酶抑制剂的药物开发范式

Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential

前列腺肿瘤细胞对外部雄激素依赖性的丧失与葡萄糖醛酸化潜能的升高有关。

Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis

Dnmt3b 的甲基化非依赖性抑制促进了 Dnmt3a 在小鼠 MYC 诱导的 T 细胞淋巴瘤发生中的致癌活性

Advances in Hyaluronan Biology: Signaling, Regulation, and Disease Mechanisms

透明质酸生物学进展：信号传导、调控和疾病机制