日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Drug-bound outward-facing conformation of a heterodimeric ABC exporter suggests a putative mechanism of drug translocation

异二聚体ABC转运蛋白与药物结合后呈现的外向构象提示了一种可能的药物转运机制。

Tang, Qingyu; Sinclair, Matt; Bisignano, Paola; Zhang, Yunsen; Tajkhorshid, Emad; Mchaourab, Hassane S

Lipid-mediated mechanism of drug extrusion by a heterodimeric ABC exporter

异二聚体ABC外排蛋白介导的药物外排机制

Tang, Qingyu; Sinclair, Matt; Bisignano, Paola; Zhang, Yunsen; Tajkhorshid, Emad; Mchaourab, Hassane S

A Gram-negative-selective antibiotic that spares the gut microbiome.

一种对革兰氏阴性菌具有选择性的抗生素,不会破坏肠道微生物群

Muñoz Kristen A, Ulrich Rebecca J, Vasan Archit K, Sinclair Matt, Wen Po-Chao, Holmes Jessica R, Lee Hyang Yeon, Hung Chien-Che, Fields Christopher J, Tajkhorshid Emad, Lau Gee W, Hergenrother Paul J

Integrative analysis of pathogenic variants in glucose-6-phosphatase based on an AlphaFold2 model

基于AlphaFold2模型的葡萄糖-6-磷酸酶致病变异的整合分析

Sinclair, Matt; Stein, Richard A; Sheehan, Jonathan H; Hawes, Emily M; O'Brien, Richard M; Tajkhorshid, Emad; Claxton, Derek P

The Role of Protein-Lipid Interactions in Priming the Bacterial Translocon

蛋白质-脂质相互作用在启动细菌转位子中的作用

Sinclair, Matt; Tajkhorshid, Emad

Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter

不对称构象和脂质相互作用塑造了异二聚体ABC转运蛋白的ATP偶联循环

Tang, Qingyu; Sinclair, Matt; Hasdemir, Hale S; Stein, Richard A; Karakas, Erkan; Tajkhorshid, Emad; Mchaourab, Hassane S