Singer Natalie V相关文献与解析，生知库 | 链接生命科学的每一步

A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activity

一种小分子c-Rel抑制剂可降低T细胞的同种异体活化，且不影响其抗肿瘤活性。

Shono, Yusuke; Tuckett, Andrea Z; Ouk, Samedy; Liou, Hsiou-Chi; Altan-Bonnet, Grégoire; Tsai, Jennifer J; Oyler, Jennifer E; Smith, Odette M; West, Mallory L; Singer, Natalie V; Doubrovina, Ekaterina; Pankov, Dmitry; Undhad, Chandresh V; Murphy, George F; Lezcano, Cecilia; Liu, Chen; O'Reilly, Richard J; van den Brink, Marcel R M; Zakrzewski, Johannes L

肿瘤

Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells.

自噬基因Atg16L1可阻止树突状细胞介导的致命性T细胞同种异体反应

期刊:Immunity

影响因子:26.3

doi:10.1016/j.immuni.2014.09.011

Hubbard-Lucey Vanessa M, Shono Yusuke, Maurer Katie, West Mallory L, Singer Natalie V, Ziegler Carly G K, Lezcano Cecilia, Motta Ana Carolina Fragoso, Schmid Karin, Levi Samuel M, Murphy George F, Liu Chen, Winkler Jeffrey D, Amaravadi Ravi K, Rogler Gerhard, Dickinson Anne M, Holler Ernst, van den Brink Marcel R M, Cadwell Ken

The central nervous system is a target of acute graft versus host disease in mice

小鼠急性移植物抗宿主病的靶器官是中枢神经系统。

期刊:Blood

影响因子:23.1

doi:10.1182/blood-2012-09-456590

Hartrampf, Steffen; Dudakov, Jarrod A; Johnson, Linda K; Smith, Odette M; Tsai, Jennifer; Singer, Natalie V; West, Mallory L; Hanash, Alan M; Albert, Michael H; Liu, Bingfang; Toth, Miklos; van den Brink, Marcel R M

神经科学

发表日期：2013

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PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating GVHD

PLZF赋予供体T细胞效应功能，既能维持移植物抗肿瘤效应，又能减轻移植物抗宿主病（GVHD）。

期刊:Cancer Research

影响因子:16.6

doi:10.1158/0008-5472.CAN-12-4699

Ghosh, Arnab; Holland, Amanda M; Dogan, Yildirim; Yim, Nury L; Rao, Uttam K; Young, Lauren F; West, Mallory L; Singer, Natalie V; Lee, Hae; Na, Il-Kang; Tsai, Jennifer J; Jenq, Robert R; Penack, Olaf; Hanash, Alan M; Lezcano, Cecilia; Murphy, George F; Liu, Chen; Sadelain, Michel; Sauer, Martin G; Sant'angelo, Derek; van den Brink, Marcel R M

Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease

白细胞介素-22可保护肠道干细胞免受免疫介导的组织损伤，并调节其对移植物抗宿主病的敏感性。

期刊:Immunity

影响因子:26.3

doi:10.1016/j.immuni.2012.05.028

Hanash, Alan M; Dudakov, Jarrod A; Hua, Guoqiang; O'Connor, Margaret H; Young, Lauren F; Singer, Natalie V; West, Mallory L; Jenq, Robert R; Holland, Amanda M; Kappel, Lucy W; Ghosh, Arnab; Tsai, Jennifer J; Rao, Uttam K; Yim, Nury L; Smith, Odette M; Velardi, Enrico; Hawryluk, Elena B; Murphy, George F; Liu, Chen; Fouser, Lynette A; Kolesnick, Richard; Blazar, Bruce R; van den Brink, Marcel R M

Extrathymic development of murine T cells after bone marrow transplantation

小鼠骨髓移植后胸腺外T细胞的发育

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI60630

Holland, Amanda M; Zakrzewski, Johannes L; Tsai, Jennifer J; Hanash, Alan M; Dudakov, Jarrod A; Smith, Odette M; West, Mallory L; Singer, Natalie V; Brill, Jessie; Sun, Joseph C; van den Brink, Marcel R M

Proximal Plantar Plate of Lesser Toe Metatarsophalangeal Joint Vascular Supply

小趾跖趾关节近端跖板血管供应

Presence of Neovascularization in Torn Plantar Plates of the Lesser Metatarsophalangeal Joints

小跖趾关节撕裂的跖板中新生血管的出现

Microvasculature of the Plantar Plate Using Nano-Computed Tomography

利用纳米计算机断层扫描技术研究足底板的微血管系统

A small-molecule c-Rel inhibitor reduces alloactivation of T cells without compromising antitumor activity

一种小分子c-Rel抑制剂可降低T细胞的同种异体活化，且不影响其抗肿瘤活性。

Autophagy gene Atg16L1 prevents lethal T cell alloreactivity mediated by dendritic cells.

自噬基因Atg16L1可阻止树突状细胞介导的致命性T细胞同种异体反应

The central nervous system is a target of acute graft versus host disease in mice

小鼠急性移植物抗宿主病的靶器官是中枢神经系统。

PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating GVHD

PLZF赋予供体T细胞效应功能，既能维持移植物抗肿瘤效应，又能减轻移植物抗宿主病（GVHD）。

Interleukin-22 protects intestinal stem cells from immune-mediated tissue damage and regulates sensitivity to graft versus host disease

白细胞介素-22可保护肠道干细胞免受免疫介导的组织损伤，并调节其对移植物抗宿主病的敏感性。

Extrathymic development of murine T cells after bone marrow transplantation

小鼠骨髓移植后胸腺外T细胞的发育