日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

RAS-GTP Inhibition Overcomes Acquired Resistance to KRASG12C Inhibitors Mediated by Oncogenic and Wild-Type RAS Activation in Non-Small Cell Lung Cancer

RAS-GTP抑制剂可克服非小细胞肺癌中由致癌性和野生型RAS激活介导的对KRASG12C抑制剂的获得性耐药性

Solanki, Hitendra S; Shah, Harshit; Imbody, Denis; Desai, Bina; Kato, Ryoji; Miroshnychenko, Daria; Stern, Yaakov E; Majumder, Anurima; Sarcar, Bhaswati; Xieraili, Aobuli; Stewart, Paul A; Fang, Bin; Zhang, Yonghong; Yao, Jiqiang; Darville, Lancia N; Koomen, John M; Rix, Uwe; Evans, James W; Yang, Yu Chi; Ahler, Ethan; Marusyk, Andriy; Singh, Mallika; Aronchik, Ida; Haura, Eric B

Leveraging Observation Units for Disaster Response: Cases of Efficient Care Delivery in Disaster Incidents

利用观察单元进行灾害应对:灾害事件中高效护理服务的案例

Emeli, Iyesatta M; Singh, Mallika; Hwang, Esther; Husain, Irfan; Caspers, Christopher; Isakov, Alexander; Ross, Michael A

State of the Art: Observation Units in the Emergency Department, an Interim Practice Update and Policy Review

最新进展:急诊科观察病房的中期实践更新和政策回顾

Caspers, Christopher; Singh, Mallika; Baugh, Christopher W; Southerland, Lauren T; Bischof, Jason J; Weinberger, Andrew; Singh, Hardeep; Hughes, George B; Wheatley, Matthew; Ross, Michael A

Coexistent PTEN and PIK3CA alterations hyperactivate mTORC1 signaling in endometrial cancers and cause their selective sensitivity to mTORC1 inhibition

PTEN 和 PIK3CA 的共存改变会过度激活子宫内膜癌中的 mTORC1 信号通路,并导致其对 mTORC1 抑制剂的选择性敏感性。

Solomon, Hilla; Mukherjee, Radha; Yang, Yu Chi; Meredith, Julia; Schram, Alison M; Yi, Sang Ah; Chen, Xiaoping; Tribuzio, Michael; Gundlapalli, Harika; Meyerowitz, Justin; de Stanchina, Elisa; Weigelt, Britta; An, Heeseon; Barry, Simon T; Smith, Jacqueline A M; Singh, Mallika; Rosen, Neal

From crisis to recovery: Exploring the demand surge for mental health services in Alberta, Canada-A document-based policy analysis with an illustrative supply-demand simulation (2023-2024)

从危机到复苏:探索加拿大阿尔伯塔省心理健康服务需求激增——基于文件的政策分析及供需模拟示例(2023-2024)

Adegoke, Kola; Adegoke, Abimbola; Dawodu, Deborah; Bayowa, Ayoola; Adekoya, Akorede; Kayode, Temitope; Singh, Mallika; Durojaye, Olajide Alfred; Aluko, Abiodun Isola; Adegoke, Adeyinka

Correction: Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers

更正:RMC-6236对RAS-GTP抑制在RAS驱动型癌症中的转化和治疗评估

Jiang, Jingjing; Jiang, Lingyan; Maldonato, Benjamin J; Wang, Yingyun; Holderfield, Matthew; Aronchik, Ida; Winters, Ian P; Salman, Zeena; Blaj, Cristina; Menard, Marie; Brodbeck, Jens; Chen, Zhe; Wei, Xing; Rosen, Michael J; Gindin, Yevgeniy; Lee, Bianca J; Evans, James W; Chang, Stephanie; Wang, Zhican; Seamon, Kyle J; Parsons, Dylan; Cregg, James; Marquez, Abby; Tomlinson, Aidan C A; Yano, Jason K; Knox, John E; Quintana, Elsa; Aguirre, Andrew J; Arbour, Kathryn C; Reed, Abby; Gustafson, W Clay; Gill, Adrian L; Koltun, Elena S; Wildes, David; Smith, Jacqueline A M; Wang, Zhengping; Singh, Mallika

T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma.

胰腺导管腺癌临床前模型中 RAS(ON) 多选择性抑制对肿瘤消退和完全缓解的 T 细胞依赖性

Orlen Margo, Vostrejs William P, Sor Rina, McDevitt Jayne C, Kemp Samantha B, Kim Il-Kyu, Kramer Adam B, Tovbis Shifrin Nataliya, Markosyan Nune, Clendenin Cynthia, Singh Mallika, Quintana Elsa, Menard Marie, Vonderheide Robert H, Stanger Ben Z

The Bi-steric, mTORC1-Selective Inhibitor, RMC-5552, in Advanced Solid Tumors: A Phase 1 Trial

双位阻 mTORC1 选择性抑制剂 RMC-5552 在晚期实体瘤中的应用:一项 1 期临床试验

Schram, Alison M; Naqash, Abdul Rafeh; Haura, Eric B; Riess, Jonathan W; Ulahannan, Susanna V; Ou, Sai-Hong I; Munster, Pamela N; Cheng, Michael L; Gustafson, W Clay; Bitman, Bojena; Friedman, Robert; Penn, Ruth; Kar, Sumit; Seshadri, Vidya; Wang, Zhican; Tao, Lin; Yang, Yu Chi; Singh, Mallika; Burris, Howard A; Meyerowitz, Justin G

In Situ RAS:RAF Binding Correlates with Response to KRASG12C Inhibitors in KRASG12C-Mutant Non-Small Cell Lung Cancer.

原位 RAS:RAF 结合与 KRASG12C 突变型非小细胞肺癌对 KRASG12C 抑制剂的反应相关

Kato Ryoji, Solanki Hitendra S, Ozakinci Hilal, Desai Bina, Gundlapalli Harika, Yang Yu Chi, Aronchik Ida, Singh Mallika, Johnson Joseph, Marusyk Andriy, Boyle Theresa A, Haura Eric B

Sagittal Orientation of the Acetabulum and Its Relationship to Spinopelvic Alignment: Three-Dimensional Assessment of 3700 Individuals

髋臼矢状面方向及其与脊柱骨盆排列的关系:3700例个体的三维评估

Hatem, Munif A; Movahhedi, Mohammadreza; Kim, Jin-Young; Singh, Mallika; De Silva, Shanika A; Bixby, Sarah; Kim, Young-Jo; Novais, Eduardo N; Kiapour, Ata M