日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

DNA2 and FANCM function in two distinctive pathways in disrupting TERRA R-loops and suppressing replication stress at ALT telomeres

DNA2 和 FANCM 通过两条不同的途径破坏 TERRA R 环并抑制 ALT 端粒的复制压力。

Ragupathi, Ashwin; Abid, Heba Z; Chen, Yun; Zhao, Rongwei; Kosiyatrakul, Settapong T; Yetil, Derin I; Neiswander, Julia; Feltman, Rachel; Thomas, Shannon; Yusupov, Benjamin; Singh, Manrose; Zheng, Li; Shen, Binghui; Zhang, Huaiying; Chu, Hsueh-Ping C; Schildkraut, Carl L; Xiao, Ming; Zhang, Dong

A case of malignant transformation of a serous borderline ovarian tumor effectively treated with BRAF/MEK inhibitor combination

一例浆液性交界性卵巢肿瘤恶性转化,采用BRAF/MEK抑制剂联合治疗后疗效显著。

Singh, Manrose; Cornwell, Samantha; Shaddaie, Ariel; Wachsmuth, Leah; Ragupathi, Ashwin; Salichos, Leonidas; Nissel-Horowitz, Sandra; Roy, Rajasree; Plummer, Maria; Zhang, Dong; Mehrotra, Bhoomi

Targeting the BRCA1/2 deficient cancer with PARP inhibitors: Clinical outcomes and mechanistic insights

利用PARP抑制剂靶向BRCA1/2缺陷型癌症:临床结果和机制解析

Ragupathi, Ashwin; Singh, Manrose; Perez, Alexis M; Zhang, Dong

Demystifying the Relationship Between Metformin, AMPK, and Doxorubicin Cardiotoxicity

揭秘二甲双胍、AMPK和阿霉素心脏毒性之间的关系

Singh, Manrose; Nicol, Akito T; DelPozzo, Jaclyn; Wei, Jia; Singh, Mandeep; Nguyen, Tony; Kobayashi, Satoru; Liang, Qiangrong

Interrelated Mechanism by Which the Methide Quinone Celastrol, Obtained from the Roots of Tripterygium wilfordii, Inhibits Main Protease 3CL(pro) of COVID-19 and Acts as Superoxide Radical Scavenger

从雷公藤根中提取的甲醚醌类化合物雷公藤内酯醇抑制新冠病毒主要蛋白酶3CL(pro)并作为超氧自由基清除剂发挥作用的相互关联机制

Caruso, Francesco; Singh, Manrose; Belli, Stuart; Berinato, Molly; Rossi, Miriam

The Effects of Genetic and Epigenetic Alterations of BARD1 on the Development of Non-Breast and Non-Gynecological Cancers

BARD1基因和表观遗传改变对非乳腺癌和非妇科癌症发展的影响

Watters, Andrea K; Seltzer, Emily S; MacKenzie, Danny Jr; Young, Melody; Muratori, Jonathan; Hussein, Rama; Sodoma, Andrej M; To, Julie; Singh, Manrose; Zhang, Dong

Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer.

ALK重排肺癌对第一代和第二代ALK抑制剂产生耐药性的分子机制

Gainor Justin F, Dardaei Leila, Yoda Satoshi, Friboulet Luc, Leshchiner Ignaty, Katayama Ryohei, Dagogo-Jack Ibiayi, Gadgeel Shirish, Schultz Katherine, Singh Manrose, Chin Emily, Parks Melissa, Lee Dana, DiCecca Richard H, Lockerman Elizabeth, Huynh Tiffany, Logan Jennifer, Ritterhouse Lauren L, Le Long P, Muniappan Ashok, Digumarthy Subba, Channick Colleen, Keyes Colleen, Getz Gad, Dias-Santagata Dora, Heist Rebecca S, Lennerz Jochen, Sequist Lecia V, Benes Cyril H, Iafrate A John, Mino-Kenudson Mari, Engelman Jeffrey A, Shaw Alice T