A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors
连接酶 IV 缺乏的人类 iPSC 模型揭示了 NHEJ 介导的 DSB 修复在诱导性多能干细胞和新兴造血祖细胞的存活和基因组稳定性中的重要作用
期刊:Cell Death and Differentiation
影响因子:13.7
doi:10.1038/cdd.2013.44
K Tilgner, I Neganova, I Moreno-Gimeno, J Y Al-Aama, D Burks, S Yung, C Singhapol, G Saretzki, J Evans, V Gorbunova, A Gennery, S Przyborski, M Stojkovic, L Armstrong, P Jeggo, M Lako
