日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Whole-genome CRISPR-Cas9 knockout screens identify SHOC2 as a genetic dependency in NRAS-mutant melanoma

全基因组 CRISPR-Cas9 敲除筛选鉴定出 SHOC2 是 NRAS 突变型黑色素瘤的遗传依赖性基因

Gu, Andrea Y; Lee, Tet Woo; Khan, Aziza; Zhang, Xuenan; Hunter, Francis W; Singleton, Dean C; Jamieson, Stephen M F

Clinical relevance and therapeutic predictive ability of hypoxia biomarkers in head and neck cancer tumour models

缺氧生物标志物在头颈癌肿瘤模型中的临床意义和治疗预测能力

Lee, Tet Woo; Singleton, Dean C; Harms, Julia K; Lu, Man; McManaway, Sarah P; Lai, Amy; Tercel, Moana; Pruijn, Frederik B; Macann, Andrew M J; Hunter, Francis W; Wilson, William R; Jamieson, Stephen M F

Megakaryocyte maturation involves activation of the adaptive unfolded protein response.

巨核细胞成熟涉及适应性未折叠蛋白反应的激活

Faiz Mifra, Kalev-Zylinska Maggie L, Dunstan-Harrison Caitlin, Singleton Dean C, Hay Michael P, Ledgerwood Elizabeth C

In vitro breast cancer models for studying mechanisms of resistance to endocrine therapy

用于研究内分泌治疗耐药机制的体外乳腺癌模型

Cheng, Gary J; Leung, Euphemia Y; Singleton, Dean C

Patient-Derived Xenograft and Organoid Models for Precision Medicine Targeting of the Tumour Microenvironment in Head and Neck Cancer

患者来源的异种移植和类器官模型用于精准治疗头颈癌肿瘤微环境

Lee, Tet Woo; Lai, Amy; Harms, Julia K; Singleton, Dean C; Dickson, Benjamin D; Macann, Andrew M J; Hay, Michael P; Jamieson, Stephen M F

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor

LP99:首个选择性BRD7/9溴结构域抑制剂的发现与合成

Clark, Peter G K; Vieira, Lucas C C; Tallant, Cynthia; Fedorov, Oleg; Singleton, Dean C; Rogers, Catherine M; Monteiro, Octovia P; Bennett, James M; Baronio, Roberta; Müller, Susanne; Daniels, Danette L; Méndez, Jacqui; Knapp, Stefan; Brennan, Paul E; Dixon, Darren J

Bystander or no bystander for gene directed enzyme prodrug therapy

基因导向酶前药疗法:旁观者效应还是非旁观者效应

Dachs, Gabi U; Hunt, Michelle A; Syddall, Sophie; Singleton, Dean C; Patterson, Adam V