日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel humanized loss-of-function NF1 mouse model of juvenile myelomonocytic leukemia.

新型人源化功能缺失型 NF1 小鼠幼年型骨髓单核细胞白血病模型。

Sinha Roshani, Patil Rachana Vinay, Romano Rosa, Sharma Devesh, Lee Esmond, Perriman Rhonda, Takeda Saori, Lesch Benjamin J, Yao Zhenyu, Liu Y Lucy, Cromer M Kyle, Porteus Matthew H, Bertaina Alice

Combinatorial base editing couples disease correction with lineage amplification in hematopoietic stem and progenitor cells

组合碱基编辑技术将疾病矫正与造血干细胞和祖细胞的谱系扩增相结合

Jia, Kun; Soupene, Eric; Sinha, Roshani; Lesch, Benjamin J; Pendergast, Michael A; Choi, Rachel; Zhang, Xinyi; Foppiani, Elisabetta M; Kostamo, Zachary; Chu, Simon N; Sharma, Devesh; Yu, Xinjie; Cordero, Marco; Walters, Mark C; MacKenzie, Tippi C; Sheehan, Vivien A; Cromer, M Kyle

Protocol for efficient CRISPR/AAV-mediated genome editing and erythroid differentiation of human hematopoietic stem and progenitor cells.

利用 CRISPR/AAV 介导的基因组编辑和人类造血干细胞及祖细胞红系分化的有效方案

Sharma Devesh, Sinha Roshani, Lesch Benjamin J, Cromer M Kyle

Epigenetic Profiling of PTPN11 Mutant JMML Hematopoietic Stem and Progenitor Cells Reveals an Aberrant Histone Landscape

PTPN11突变型JMML造血干细胞和祖细胞的表观遗传学分析揭示了异常的组蛋白谱。

Sinha, Roshani; Dvorak, Mai; Ganesan, Ananthakrishnan; Kalesinskas, Larry; Niemeyer, Charlotte M; Flotho, Christian; Sakamoto, Kathleen M; Lacayo, Norman; Patil, Rachana Vinay; Perriman, Rhonda; Cepika, Alma-Martina; Liu, Yunying Lucy; Kuo, Alex; Utz, Paul J; Khatri, Purvesh; Bertaina, Alice