日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Unveiling Cas8 dynamics and regulation within a transposon-encoded Cascade-TniQ complex

揭示转座子编码的Cascade-TniQ复合物中Cas8的动态变化和调控

Patel, Amun C; Sinha, Souvik; Arantes, Pablo R; Palermo, Giulia

Graph Attention Neural Networks Reveal TnsC Filament Assembly in a CRISPR-Associated Transposon

图注意力神经网络揭示了 CRISPR 相关转座子中 TnsC 丝状体的组装

Pindi, Chinmai; Ahsan, Mohd; Sinha, Souvik; Palermo, Giulia

Dimerization of the deaminase domain and locking interactions with Cas9 boost base editing efficiency in ABE8e

脱氨酶结构域的二聚化以及与Cas9的锁定相互作用增强了ABE8e的碱基编辑效率

Arantes, Pablo R; Chen, Xiaoyu; Sinha, Souvik; Saha, Aakash; Patel, Amun C; Sample, Matthew; Nierzwicki, Łukasz; Lapinaite, Audrone; Palermo, Giulia

Unveiling the RNA-mediated allosteric activation discloses functional hotspots in CRISPR-Cas13a.

揭示 RNA 介导的变构激活揭示了 CRISPR-Cas13a 中的功能热点

Sinha Souvik, Molina Vargas Adrian M, Arantes Pablo R, Patel Amun, O'Connell Mitchell R, Palermo Giulia

Graph theory approaches for molecular dynamics simulations

图论方法在分子动力学模拟中的应用

Patel, Amun C; Sinha, Souvik; Palermo, Giulia

Machines on Genes through the Computational Microscope

通过计算显微镜观察基因上的机器

Sinha, Souvik; Pindi, Chinmai; Ahsan, Mohd; Arantes, Pablo R; Palermo, Giulia

RNA-mediated Allosteric Activation in CRISPR-Cas13a

CRISPR-Cas13a 中 RNA 介导的变构激活

Sinha, Souvik; Molina Vargas, Adrian M; Arantes, Pablo R; Patel, Amun; O'Connell, Mitchell R; Palermo, Giulia

Disruption of electrostatic contacts in the HNH nuclease from a thermophilic Cas9 rewires allosteric motions and enhances high-temperature DNA cleavage

嗜热Cas9破坏HNH核酸酶中的静电接触,重塑变构运动,增强高温下DNA的切割能力。

Belato, Helen B; Norbrun, Carmelissa; Luo, Jinping; Pindi, Chinmai; Sinha, Souvik; D'Ordine, Alexandra M; Jogl, Gerwald; Palermo, Giulia; Lisi, George P

HKT1;5 Transporter Gene Expression and Association of Amino Acid Substitutions With Salt Tolerance Across Rice Genotypes

HKT1;5转运蛋白基因表达及氨基酸替换与水稻基因型耐盐性的关系

Shohan, Mohammad Umer Sharif; Sinha, Souvik; Nabila, Fahmida Habib; Dastidar, Shubhra Ghosh; Seraj, Zeba I

TBIO-10. PEDIATRIC TARGETED THERAPY 2.0: DEVELOPMENT OF PERSONALIZED PEDIATRIC ONCOLOGY

TBIO-10. 儿科靶向治疗 2.0:个性化儿科肿瘤学的发展

Vargas, Adrian M Molina; Osborn, Raven; Sinha, Souvik; Arantes, Pablo R; Patel, Amun; Dewhurst, Stephen; Palermo, Giulia; O'Connell, Mitchell R; Ecker, Jonas; Selt, Florian; Sahm, Felix; Capper, David; Korshunov, Andrey; Grund, Kerstin; Dikow, Nicola; Sutter, Christian; van Tilburg, Cornelis; Witt, Hendrik; von Deimling, Andreas; Jones, David T W; Pfister, Stefan M; Witt, Olaf; Milde, Till